Making Emergency Use of Experimental Vaccines Safer

• Published in: AMA journal of ethics Vol. 22; no. 1; p. E43
• Main Authors: Asundi, Archana, Bhadelia, Nahid
• Format: Journal Article
• Language: English
• Published: United States 01.01.2020
• Subjects: Altruism; Disease Outbreaks - ethics; Drug Approval; Emergencies; Health Services Accessibility - ethics; Hemorrhagic Fever, Ebola - prevention & control; Humans; Patient Safety; Research Subjects; Risk; Vaccination - ethics; Vaccines - adverse effects; Vulnerable Populations

Ethical and logistical challenges of deploying experimental vaccines in humanitarian emergencies are exacerbated by a paucity of safety and efficacy data. For outbreaks caused by pathogens with high mortality rates and few treatments, such as Ebola virus disease, not offering access to experimental...