NF546 [4,4′-(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-α,α′-diphosphonic Acid) Tetrasodium Salt] Is a Non-Nucleotide P2Y11 Agonist and Stimulates Release of Interleukin-8 from Human Monocyte-Derived Dendritic Cells - Meis, Sabine; Hamacher, Alexandra; Hongwiset, Darunee; Marzian, Claudia; Wiese, Michael; Eckstein, Niels; Royer, Hans-Dieter; Communi, Didier; Boeynaems, Jean-Marie; Hausmann, Ralf; Schmalzing, Günther; Kassack, Matthias U. (The Journal of pharmacology and experimental therapeutics, 2010)
Keywords: Calcium - metabolism; Cell Culture Techniques; Cell Line, Tumor; Cloning, Molecular; Cyclic AMP - metabolism; Dendritic Cells - drug effects; Dendritic Cells - immunology; Dendritic Cells - metabolism; Diphosphonates - pharmacology; Dose-Response Relationship, Drug; Humans; Interleukin-8 - metabolism; Ligands; Naphthalenesulfonates - pharmacology; Protein Binding; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2 - metabolism; Receptors, Purinergic P2X; Recombinant Proteins; Transfection; Tricine; ATPγS; IL-4; IL-8; IL-12; LPS; NF157; DMEM; TSP-1; 2-MeSATP; NF546; ADPβS; NF340; BzATP; DC; ELISA