A Computerized Physician Order Entry Set Designed to Improve Safety of Intravenous Haloperidol Utilization A Retrospective Study in Agitated Hospitalized Patients

• Published in: Drug safety Vol. 35; no. 9; pp. 725 - 731
• Main Authors: Muzyk, Andrew J., Rivelli, Sarah K., Jiang, Wei, Heinz, Heather, Rayfield, Amber, Gagliardi, Jane P.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.09.2012; Adis International
• Subjects: Biological and medical sciences; Cardiac dysrhythmias; Cardiology. Vascular system; Drug Safety and Pharmacovigilance; Drug toxicity and drugs side effects treatment; Drugs; Heart; Hospitals; Magnesium; Medical sciences; Medicine & Public Health; Mitigation; Mortality; Pharmacology. Drug treatments; Pharmacology/Toxicology; Risk factors; Short Communication; Toxicity: cardiovascular system; Haloperidol; Drug Utilization Review; Computerize Physician Order Entry System; Computerize Physician Order Entry; Computerize Provider Order Entry; Human; QT interval; Agitation; Intravenous administration; Arrhythmia; Neuroleptic; Psychotropic; Health staff; Toxicity; Dopamine antagonist; Sudden death; Physician; Cardiovascular disease; Hospital environment; Butyrophenone derivatives; Excitability disorder; Retrospective; D2 Dopamine receptor; Heart disease; Torsades de pointes; Safety; Computer aid

Background: Intravenous haloperidol can increase the risk for corrected QT (QTc) interval prolongation, torsades de pointes (TdP) and sudden death. Objective: The purpose of this study was to examine the effects of implementation of a computerized physician order entry (CPOE) set on adherence to mon...