Design, integration, and commissioning of the first linac for image guided hadron therapy prototype
The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key...
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Published in | Physical review. Accelerators and beams Vol. 27; no. 5 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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01.05.2024
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Abstract | The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key functional aspects of the full energy accelerator) has been designed and tested in parallel with the preparation work for a full-scale system. The LIGHT prototype construction, installation, and commissioning with beam allowed the identification of technical gaps and design improvements before the transfer to a medical device implementation. This paper gives a comprehensive summary of the design and integration aspects and presents for the first time the results achieved with the LIGHT prototype that was installed and commissioned on CERN premises in the years 2015–2019. Published by the American Physical Society 2024 |
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AbstractList | The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key functional aspects of the full energy accelerator) has been designed and tested in parallel with the preparation work for a full-scale system. The LIGHT prototype construction, installation, and commissioning with beam allowed the identification of technical gaps and design improvements before the transfer to a medical device implementation. This paper gives a comprehensive summary of the design and integration aspects and presents for the first time the results achieved with the LIGHT prototype that was installed and commissioned on CERN premises in the years 2015–2019. Published by the American Physical Society 2024 |
ArticleNumber | 054701 |
Author | Barreto, Cristovao Andre Dionisio Aguilera Murciano, Debora Healy, Alisa Baccigalupi, Carlo Myers, Stephen Cerv, Matevz Esposito, Luigi Salvatore Magnoni, Stefano Mellace, Claudio Caldara, Michele Fink, Daniel Roman Concha, Diomedes Valloni, Alessandra Vazquez Rivera, Daniel Khan, Vasim Castorina, Giovanni Galizzi, Francesco Murteira, Diogo Stachyra, Katarzyna Madoulaud, Lucile Magrin, Guillaume Salveter, Friederike Jeff, Adam Navarro Quirante, Luis Leal Seixas Correia, Miguel Benot Morell, Alfonso Gallas Torreira, Manuel Ballestrero, Sergio Stabile, Pierpaolo Breitenfeldt, Martin D’Auria, Gerardo Soriano Guillen, Dario Samochkine, Alexandre Levy, Gabriel Nadig, Patricio De Michele, Giovanni Ungaro, Donatella Gibson, Stephen Rejas, Christopher Aumon, Sandra Zannini, Carlo Bellorini, François Nardulli, Jacopo Rutter, Theodore Ivanisenko, Yevgeniy Sanchez Gonzalez, Andres Fabich, Adrian Moser, Roland Giunta, Marina Gonzalez Fernandez, Maria del Mar Conde Fernandez, Beatriz Fusco, Yoann Bouhired, Denia Bonomi, Rossana Dimov, Veliko Vallé, Mar |
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Cites_doi | 10.1103/PhysRevAccelBeams.20.080102 10.1016/j.nima.2003.07.062 10.1016/S0168-9002(97)00972-8 10.1103/PhysRevAccelBeams.23.020102 |
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References | M. Vretenar (PhysRevAccelBeams.27.054701Cc13R1) 2016 PhysRevAccelBeams.27.054701Cc14R1 U. Amaldi (PhysRevAccelBeams.27.054701Cc1R1) 2009 D. Ungaro (PhysRevAccelBeams.27.054701Cc9R1) 2016 PhysRevAccelBeams.27.054701Cc29R1 G. De Michele (PhysRevAccelBeams.27.054701Cc34R1) 2018 R. Moser (PhysRevAccelBeams.27.054701Cc24R1) 2017 M. Vretenar (PhysRevAccelBeams.27.054701Cc8R1) 2014 A. Jeff (PhysRevAccelBeams.27.054701Cc31R1) 2018 R. W. Hamm (PhysRevAccelBeams.27.054701Cc3R1) 1991 F. Galizzi (PhysRevAccelBeams.27.054701Cc27R1) 2018 A. Degiovanni (PhysRevAccelBeams.27.054701Cc33R1) 2018 U. Amaldi (PhysRevAccelBeams.27.054701Cc4R1) 2007 S. Benedetti (PhysRevAccelBeams.27.054701Cc30R1) 2022 R. Moser (PhysRevAccelBeams.27.054701Cc23R1) 2017 V. Dimov (PhysRevAccelBeams.27.054701Cc32R1) 2018 V. Khan (PhysRevAccelBeams.27.054701Cc10R1) 2018 PhysRevAccelBeams.27.054701Cc6R1 PhysRevAccelBeams.27.054701Cc5R1 V. G. Vaccaro (PhysRevAccelBeams.27.054701Cc7R1) 2008 |
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