Design, integration, and commissioning of the first linac for image guided hadron therapy prototype

The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key...

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Published inPhysical review. Accelerators and beams Vol. 27; no. 5
Main Authors Degiovanni, Alberto, De Michele, Giovanni, Bonomi, Rossana, Cabaleiro Magallanes, Francisco, Caldara, Michele, Dimov, Veliko, Esposito, Marco, Fink, Daniel, Gallas Torreira, Manuel, Ivanisenko, Yevgeniy, Jeff, Adam, Magnoni, Stefano, Navarro Quirante, Luis, Pavetits, Hannes, Valloni, Alessandra, Adam, Joël, Aguilera Murciano, Debora, Aumon, Sandra, Baccigalupi, Carlo, Baiguera Tambutti, Laura, Bailly, Sylvain, Ballestrero, Sergio, Bellorini, François, Benedetti, Stefano, Benot Morell, Alfonso, Bouhired, Denia, Breitenfeldt, Martin, Candolfi, Sylvain, Castorina, Giovanni, Cerv, Matevz, Conde Fernandez, Beatriz, D’Auria, Gerardo, Barreto, Cristovao Andre Dionisio, Esposito, Luigi Salvatore, Fabich, Adrian, Fanella, Stefano, Fazio, Daniel, Fusco, Yoann, Galizzi, Francesco, Gibson, Stephen, Giunta, Marina, Gonzalez Fernandez, Maria del Mar, Gradassi, Paolo, Healy, Alisa, Khan, Vasim, Kobzeva, Lisa, Leal Seixas Correia, Miguel, Levy, Gabriel, Madoulaud, Lucile, Magrin, Guillaume, Marraffa, Antonio, Mellace, Claudio, Milla Moreno, Alberto, Moser, Roland, Murteira, Diogo, Myers, Stephen, Nadig, Patricio, Nardulli, Jacopo, Nuessle, Georg, Ouerghi, Yousri, Patino Revuelta, Adriana, Paz Neira, Pablo, Rejas, Christopher, Roman Concha, Diomedes, Rutter, Theodore, Salveter, Friederike, Samochkine, Alexandre, Sanchez Gonzalez, Andres, Soriano Guillen, Dario, Stabile, Pierpaolo, Stachyra, Katarzyna, Ungaro, Donatella, Urbaniec, Bartlomiej, Vallé, Margaux, Vazquez Rivera, Daniel, Wallet, Lionel, Watts, David, Zannini, Carlo
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LanguageEnglish
Published 01.05.2024
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Abstract The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key functional aspects of the full energy accelerator) has been designed and tested in parallel with the preparation work for a full-scale system. The LIGHT prototype construction, installation, and commissioning with beam allowed the identification of technical gaps and design improvements before the transfer to a medical device implementation. This paper gives a comprehensive summary of the design and integration aspects and presents for the first time the results achieved with the LIGHT prototype that was installed and commissioned on CERN premises in the years 2015–2019. Published by the American Physical Society 2024
AbstractList The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator system. As part of the development process and of the technical validation of the concept, a reduced energy prototype linac (including all the key functional aspects of the full energy accelerator) has been designed and tested in parallel with the preparation work for a full-scale system. The LIGHT prototype construction, installation, and commissioning with beam allowed the identification of technical gaps and design improvements before the transfer to a medical device implementation. This paper gives a comprehensive summary of the design and integration aspects and presents for the first time the results achieved with the LIGHT prototype that was installed and commissioned on CERN premises in the years 2015–2019. Published by the American Physical Society 2024
ArticleNumber 054701
Author Barreto, Cristovao Andre Dionisio
Aguilera Murciano, Debora
Healy, Alisa
Baccigalupi, Carlo
Myers, Stephen
Cerv, Matevz
Esposito, Luigi Salvatore
Magnoni, Stefano
Mellace, Claudio
Caldara, Michele
Fink, Daniel
Roman Concha, Diomedes
Valloni, Alessandra
Vazquez Rivera, Daniel
Khan, Vasim
Castorina, Giovanni
Galizzi, Francesco
Murteira, Diogo
Stachyra, Katarzyna
Madoulaud, Lucile
Magrin, Guillaume
Salveter, Friederike
Jeff, Adam
Navarro Quirante, Luis
Leal Seixas Correia, Miguel
Benot Morell, Alfonso
Gallas Torreira, Manuel
Ballestrero, Sergio
Stabile, Pierpaolo
Breitenfeldt, Martin
D’Auria, Gerardo
Soriano Guillen, Dario
Samochkine, Alexandre
Levy, Gabriel
Nadig, Patricio
De Michele, Giovanni
Ungaro, Donatella
Gibson, Stephen
Rejas, Christopher
Aumon, Sandra
Zannini, Carlo
Bellorini, François
Nardulli, Jacopo
Rutter, Theodore
Ivanisenko, Yevgeniy
Sanchez Gonzalez, Andres
Fabich, Adrian
Moser, Roland
Giunta, Marina
Gonzalez Fernandez, Maria del Mar
Conde Fernandez, Beatriz
Fusco, Yoann
Bouhired, Denia
Bonomi, Rossana
Dimov, Veliko
Vallé, Mar
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Snippet The Linac for Image Guided Hadron Therapy (LIGHT) system has been developed as the first commercial high-frequency linac-based proton therapy accelerator...
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Title Design, integration, and commissioning of the first linac for image guided hadron therapy prototype
Volume 27
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