A Bayesian Approach for the Cox Proportional Hazards Model with Covariates Subject to Detection Limit

• Published in: International journal of statistics in medical research Vol. 3; no. 1; p. 32
• Main Authors: Chen, Qingxia, Wu, Huiyun, Ware, Lorraine B, Koyama, Tatsuki
• Format: Journal Article
• Language: English
• Published: Canada 31.01.2014
• Subjects: Biomarker; Lung Injury; Proportional hazards models; Detection limit; Bayesian

The research on biomarkers has been limited in its effectiveness because biomarker levels can only be measured within the thresholds of assays and laboratory instruments, a challenge referred to as a detection limit (DL) problem. In this paper, we propose a Bayesian approach to the Cox proportional...