Model-Based Clustering and Prediction With Mixed Measurements Involving Surrogate Classifiers

• Published in: Statistics in biopharmaceutical research Vol. 14; no. 3; pp. 368 - 379
• Main Authors: Shen, Hua, de Leon, Alexander R.
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 03.08.2022
• Subjects: Conditional independence; Identifiability; Joint modeling; Latent class model; Sensitivity; Specificity

Identification of underlying subpopulations to account for unobserved heterogeneity in the population is a challenging statistical problem, mainly because no explicit information about the latent classes is available. Although latent class analysis via finite mixture models is often used successfull...