Umpolung‐Enabled Divergent Dearomative Carbonylations

• Published in: Angewandte Chemie International Edition Vol. 63; no. 33; pp. e202403917 - n/a
• Main Authors: Wang, Ming‐Yang, Zeng, Wei‐Long, Chen, Lin, Yuan, Yu‐Fei, Li, Wei
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 12.08.2024
• Edition: International ed. in English
• Subjects: Alcohols; Amides; Amines; Arenes; Aromatic compounds; Benzene; Carbon cycle; Carbonylation; Carbonyls; Chemical synthesis; Chromium; Dearomatization; Dimensional tolerances; Direct conversion; Esters; Nucleophiles; Tracking control; Umpolung; Chromium; Dearomatization; Umpolung; Arenes; Carbonylation

Although dearomative functionalizations enable the direct conversion of flat aromatics into precious three‐dimensional architectures, the case for simple arenes remains largely underdeveloped owing to the high aromatic stabilization energy. We herein report a dearomative sequential addition of two n...