Monoclonal antibody 7D5 raised to cytochrome b558 of human neutrophils: immunocytochemical detection of the antigen in peripheral phagocytes of normal subjects, patients with chronic granulomatous disease, and their carrier mothers

• Published in: Blood Vol. 69; no. 5; pp. 1404 - 1408
• Main Authors: Nakamura, M, Murakami, M, Koga, T, Tanaka, Y, Minakami, S
• Format: Journal Article
• Language: English
• Published: 01.05.1987

We have established a monoclonal hybridoma clone that produces IgG1 against the cytochrome b558 of human neutrophils. The antibody 7D5, secreted by the hybridoma, bound to solubilized cytochrome b of the neutrophils but not to other proteins such as hemoglobin, myeloperoxidase, and pig cytochrome P-...