The role of periostin, eosinophil cationic protein (ECP), nesfatin-1, and NUCB2 in asthma and obesity

• Published in: The Journal of asthma Vol. 62; no. 5; p. 787
• Main Authors: Sarioglu, Nurhan, Solmaz Avcikurt, Ayla, Hismiogullari, Adnan Adil, Erel, Fuat
• Format: Journal Article
• Language: English
• Published: England 04.05.2025
• Subjects: Adult; Asthma - blood; Asthma - complications; Asthma - genetics; Calcium-Binding Proteins - blood; Calcium-Binding Proteins - genetics; Case-Control Studies; Cell Adhesion Molecules - blood; Cell Adhesion Molecules - genetics; DNA-Binding Proteins - blood; DNA-Binding Proteins - genetics; Eosinophil Cationic Protein - blood; Female; Humans; Male; Middle Aged; Nerve Tissue Proteins - blood; Nerve Tissue Proteins - genetics; Neurocalcin - blood; Neurocalcin - genetics; Nucleobindins; Obesity - blood; Obesity - complications; Obesity - genetics; Periostin; periostin; eosinophil cationic protein (ECP); nesfatin-1; obesity; Asthma

Obesity has a significant impact on asthma incidence and control. Nesfatin-1, encoded by the nucleobindin-2 (NUCB2) gene, regulates energy balance. This study aimed to evaluate NUCB2 gene polymorphism (rs757081 C > G) and its association with serum levels of nesfatin-1 and inflammatory cytokines...