Gastrointestinal Tolerability and Acute Glycemic Response of Oligosaccharides and Polysaccharides from Cellulose and Xylan in Healthy Adults: Two Double-Blinded, Randomized, Controlled, Cross-over Trials

• Published in: Journal of the American Nutrition Association Vol. 43; no. 4; p. 305
• Main Authors: Moura de Oliveira Beltrame, Daniela, Simmons, Thomas Joseph, Jenkins, Alexandra L, Dinan, Timothy, Nicholson, Thomas Joseph
• Format: Journal Article
• Language: English
• Published: United States 18.05.2024
• Subjects: Adult; Blood Glucose - analysis; Blood Glucose - drug effects; Blood Glucose - metabolism; Cellulose; Cross-Over Studies; Dietary Fiber - administration & dosage; Double-Blind Method; Feces - chemistry; Female; Gastrointestinal Diseases - chemically induced; Glycemic Index - drug effects; Humans; Insulin - blood; Male; Middle Aged; Oligosaccharides - administration & dosage; Oligosaccharides - adverse effects; Oligosaccharides - pharmacology; Plant Extracts - administration & dosage; Plant Extracts - adverse effects; Plant Extracts - pharmacology; Polysaccharides - administration & dosage; Polysaccharides - adverse effects; Polysaccharides - pharmacology; Postprandial Period; Xylans - administration & dosage; Xylans - pharmacology; Young Adult; glycemic response; Oligosaccharides; xylan; cellulose; tolerability

The aim of this study was to investigate the gastrointestinal tolerability, glycemic and insulinemic responses of Plant Fiber Extract (PFE), a mixture comprising of oligosaccharides and polysaccharides derived from cellulose and xylan. Two double-blind, randomized, controlled, cross-over trials were...