Seborrheic dermatitis and its relationship with Malassezia spp

Abstract Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific trigg...

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Published inInfectio : revista de la Asociación Colombiana de Infectología Vol. 25; no. 2; pp. 120 - 129
Main Authors Salamanca-Córdoba, Manuel Alejandro, Zambrano-Pérez, Carolina Alexandra, Mejía-Arbeláez, Carlos, Motta, Adriana, Jiménez, Pedro, Restrepo-Restrepo, Silvia, Celis-Ramírez, Adriana Marcela
Format Journal Article
LanguageEnglish
Published Asociación Colombiana de Infectología 01.06.2021
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Abstract Abstract Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that contribute to its pathophysiology. Sin ce the primary underlying pathogenic mechanisms include Malassezia proliferation and skin inflammation, the most common treatment includes topical antifungal keratolytics and anti-inflammatory agents. However, the consequences of eliminating the yeast population from the skin, the resistance profiles of Malassezia spp. and the effectivity among different groups of medications are unknown. Thus, in this review, we summarize the current knowledge on the disease´s pathophysio logy and the role of Malassezia sp. on it, as well as, the different antifungal treatment alternatives, including topical and oral treatment in the management of SD.
AbstractList Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that contribute to its pathophysiology. Sin-ce the primary underlying pathogenic mechanisms include Malassezia proliferation and skin inflammation, the most common treatment includes topical antifungal keratolytics and anti-inflammatory agents. However, the consequences of eliminating the yeast population from the skin, the resistance profiles of Malassezia spp. and the effectivity among different groups of medications are unknown. Thus, in this review, we summarize the current knowledge on the disease ́s pathophysio-logy and the role of Malassezia sp. on it, as well as, the different antifungal treatment alternatives, including topical and oral treatment in the management of SD.
Abstract Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that contribute to its pathophysiology. Sin ce the primary underlying pathogenic mechanisms include Malassezia proliferation and skin inflammation, the most common treatment includes topical antifungal keratolytics and anti-inflammatory agents. However, the consequences of eliminating the yeast population from the skin, the resistance profiles of Malassezia spp. and the effectivity among different groups of medications are unknown. Thus, in this review, we summarize the current knowledge on the disease´s pathophysio logy and the role of Malassezia sp. on it, as well as, the different antifungal treatment alternatives, including topical and oral treatment in the management of SD.
Author Zambrano-Pérez, Carolina Alexandra
Restrepo-Restrepo, Silvia
Motta, Adriana
Mejía-Arbeláez, Carlos
Jiménez, Pedro
Celis-Ramírez, Adriana Marcela
Salamanca-Córdoba, Manuel Alejandro
AuthorAffiliation Uni versidad Militar Nueva Granada
Universidad de los Andes
AuthorAffiliation_xml – sequence: 0
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Issue 2
Keywords seborrheic dermatitis
treatment
pathogenic role
Dermatitis seborréica
Malassezia
tratamiento
Language English
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Snippet Abstract Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of...
Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life....
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SubjectTerms INFECTIOUS DISEASES
malassezia
pathogenic role
seborrheic dermatitis
treatment
Title Seborrheic dermatitis and its relationship with Malassezia spp
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