Gold nanoparticle-loaded multifunctional Ti3C2Tx MXene nanosheets fabricated by in situ reduction to effectively enhance their catalase-like activity for tumor therapy

• Published in: Nano today Vol. 65; p. 102848
• Main Authors: Guo, Yuhao, Wang, Jinyu, Wu, Xiaomei, Qiao, Qianqian, Liao, Tao, Li, Linwei, Xu, Ziqiang, Zheng, Di-Wei, Kuang, Ying, Yu, Wenqian, Li, Cao
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.12.2025
• Subjects: Cascade enzyme system; Combination therapy; In situ reduction; MXene; Nanozyme; In situ reduction; Nanozyme; Cascade enzyme system; Combination therapy; MXene

Designing novel, high-performance nanozymes is essential for developing biocatalytic therapeutics, a promising therapeutic approach. In this work, gold nanoparticles (Au NPs)-loaded Ti3C2Tx MXene nanosheets (Ti3C2Tx-Au) are prepared by in situ reduction and then modified with polyethylene glycol (PE...