TEAD2 Promotes Hepatocellular Carcinoma Development and Sorafenib Resistance via TAK1 Transcriptional Activation - Zhang, Yahui; Ren, Yidan; Dong, Guoying; Jiao, Qinlian; Guo, Nan; Gao, Ping; Li, Ya; Wang, Yunshan; Zhao, Wei (Molecular cancer research, 2024)
Keywords: Animals; Carcinoma, Hepatocellular - drug therapy; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Drug Resistance, Neoplasm - genetics; Female; Gene Expression Regulation, Neoplastic - drug effects; Humans; Liver Neoplasms - drug therapy; Liver Neoplasms - genetics; Liver Neoplasms - metabolism; Liver Neoplasms - pathology; Male; MAP Kinase Kinase Kinases - genetics; MAP Kinase Kinase Kinases - metabolism; Mice; Mice, Nude; Sorafenib - pharmacology; Sorafenib - therapeutic use; TEA Domain Transcription Factors; Transcription Factors - genetics; Transcription Factors - metabolism; Transcriptional Activation; Xenograft Model Antitumor Assays