Chiral Phosphino- and (Phosphinooxy)-Substituted N-Heterocyclic Carbene Ligands and Their Application in Iridium-Catalyzed Asymmetric Hydrogenation

• Published in: Helvetica chimica acta Vol. 89; no. 8; pp. 1559 - 1573
• Main Authors: Nanchen, Steve, Pfaltz, Andreas
• Format: Journal Article
• Language: English
• Published: Zürich WILEY-VCH Verlag 01.08.2006; WILEY‐VCH Verlag; Wiley
• Subjects: asymmetric; Asymmetric catalysis; Asymmetric hydrogenation; Catalysis; Chemistry; Chemistry, Multidisciplinary; Chiral ligands; Hydrogenation; Hydrogenation, asymmetric; Iridium complexes; Physical Sciences; Science & Technology; ALLYLIC ALKYLATION; ALKENES; OLEFIN METATHESIS; OXAZOLINE LIGANDS; ENANTIOSELECTIVE HYDROGENATION; COMPLEXES

Enantiomerically pure iridium complexes with phosphino‐ and (phosphinooxy)‐substituted N‐heterocyclic carbene (NHC) ligands were synthesized. Investigation of their electronic properties showed a similar trans influence of the phosphino (or phosphinooxy) and the NHC units. The complexes were tested...