Co-amorphization of olanzapine for solubility enhancement

• Published in: Annals of medicine (Helsinki) Vol. 51; no. sup1; p. 87
• Main Authors: da Costa, Nuno F., Pinto, João F., Fernandes, Ana I.
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 21.01.2024
• Subjects: Abstract; Pharmacy

Introduction: Nowadays a significant (app. 70%) number of drugs entering the market present low solubility in water [ 1 ]. To minimize this problem, which impacts on dissolution, absorption, and therapeutic efficacy of drugs in dosage forms, several techniques have been employed, namely micronizatio...