Bioequivalence and safety of fixed-dose combination of rosuvastatin calcium and ezetimibe tablets versus coadministration of individual drugs in healthy Chinese subjects under fasting or fed state

• Published in: Naunyn-Schmiedeberg's archives of pharmacology
• Main Authors: Gao, Lei, Hu, Yue, Wu, Dandan, Zheng, Wenbo, Zhang, Hong
• Format: Journal Article
• Language: English
• Published: Germany 28.07.2025
• Subjects: Loose-dose combination; Safety; Bioequivalence; Fixed-dose combination; Rosuvastatin calcium and ezetimibe tablets

This study aimed to explore the bioequivalence and safety of the fixed-dose combination (FDC) of Rosuvastatin Calcium and Ezetimibe Tablets (10/10 mg) and loose-dose combination (LDC) formulation (rosuvastatin 10 mg + ezetimibe 10 mg) in healthy Chinese subjects under fasting or fed state. This was...