METTL14-mediated m6A RNA methylation promotes the osteogenic differentiation of pPDLSCs by regulating WNT3A

• Published in: Odontology
• Main Authors: Ma, Lan, Li, Min, Xuan, Guihong, Dai, Ying
• Format: Journal Article
• Language: English
• Published: Japan 18.04.2025
• Subjects: METTL14; Periodontitis; WNT3A; Osteogenic differentiation; PDLSCs

Periodontitis is a chronic inflammatory disease that leads to the loss of periodontal supporting tissue. Furthermore, human periodontal ligament stem cells (hPDLSCs) are identified as candidate cells for the regeneration of periodontal and alveolar bone tissues. N6-Methyladenosine (m6A) performs a v...