Bioequivalence study of perampanel oral suspension in healthy Chinese subjects under fasting and fed conditions

• Published in: Naunyn-Schmiedeberg's archives of pharmacology
• Main Authors: Li, Mupeng, Li, Yaxing, Liu, Fangfang, Huang, Qian, Yi, Xinchu, Xiao, Jing, Gan, Chunyan, Han, Yangyun, Fan, Lianlian
• Format: Journal Article
• Language: English
• Published: Germany 26.03.2025
• Subjects: Healthy subjects; Bioequivalence; Pharmacokinetics; Perampanel oral suspension

Perampanel oral suspension (Fycompa ) is indicated as adjunctive therapy for the treatment of partial-onset seizure and primary generalized tonic-clonic seizure. This study aimed to assess the bioequivalence of perampanel oral suspension and its generic under the fasting and fed conditions. A random...