Early Drain Removal is Safe in Patients With Low or Intermediate Risk of Pancreatic Fistula After Pancreaticoduodenectomy: A Multicenter, Randomized Controlled Trial

• Published in: Annals of surgery Vol. 275; no. 2; p. e307
• Main Authors: Dai, Menghua, Liu, Qiaofei, Xing, Cheng, Tian, Xiaodong, Cao, Feng, Tang, Wenbo, Lv, Shaocheng, Ma, Yongsu, Zhang, Dongxin, Kleeff, Jorg, Yang, Yinmo, Liu, Rong, He, Qiang, Li, Fei, Li, Guangming, Guo, Junchao, Liao, Quan, Zhao, Yupei
• Format: Journal Article
• Language: English
• Published: United States 01.02.2022
• Subjects: Aged; Device Removal; Drainage - instrumentation; Female; Humans; Incidence; Male; Middle Aged; Pancreatic Fistula - epidemiology; Pancreatic Fistula - prevention & control; Postoperative Complications - epidemiology; Postoperative Complications - prevention & control; Risk Assessment

This multicenter randomized controlled trial was designed to test the hypothesis that early drain removal (EDR) could decrease the incidence of grade 2 to 4 complications for patients undoing pancreaticoduodenectomy (PD) with low or intermediate risk of postoperative pancreatic fistula (POPF). The s...