Determination and validation of LJ-2698, a potent human A3 adenosine receptor antagonist, in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study - Lee, Jae-Young; Park, Ju-Hwan; Kim, Ki-Taek; Yu, Jinha; Sahu, Pramod K.; Kang, Naewon; Shin, Hyeon-Jong; Kim, Min-Hwan; Kim, Ji-Su; Yoon, In-Soo; Jeong, Lak Shin; Kim, Dae-Duk (Archives of pharmacal research, 2017)
Keywords: acetonitrile; antagonists; dose response; formic acid; humans; intravenous injection; ionization; liquid chromatography; Medicine; monitoring; nucleosides; oral administration; pharmacokinetics; Pharmacology/Toxicology; Pharmacy; purinergic receptors; rats; Research Article; statistical analysis; tandem mass spectrometry; 약학; Validation; LJ-2698; Adenosine analogues; AR antagonist; hA; Pharmacokinetics; LC–MS/MS