An open-label, positron emission tomography study to assess adenosine A2A brain receptor occupancy of vipadenant (BIIB014) at steady-state levels in healthy male volunteers - Brooks, David J; Papapetropoulos, Spyridon; Vandenhende, Francois; Tomic, Davorka; He, Ping; Coppell, Alex; O'Neill, Gilmore (Clinical neuropharmacology, 2010)
Keywords: Adenosine A2 Receptor Antagonists; Adult; Brain - diagnostic imaging; Brain - metabolism; Carbon Radioisotopes - analysis; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Models, Statistical; Positron-Emission Tomography - methods; Pyrazoles - analysis; Pyrimidines - analysis; Pyrimidines - pharmacokinetics; Radioligand Assay - methods; Triazoles - pharmacokinetics