UNACYLATED GHRELIN PLASMA LEVELS ARE LOWER AND PREDICT 5-YEAR LOW MUSCLE MASS IN ELDERLY OBESE SUBJECTS

• Published in: Nutrition (Burbank, Los Angeles County, Calif.) Vol. 87-88; p. 111316
• Main Authors: Cappellari, G. Gortan, Semolic, A., Cremasco, G., Vinci, P., Zanetti, M., Barazzoni, R.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Inc 01.08.2021; Elsevier Limited
• Subjects: Aging; bioelectrical impedance; Bioelectricity; Body fat; Body mass index; Body size; Body weight; elderly; Gender; Geriatrics; Ghrelin; health services; Indexing; Inflammation; Italy; Metabolism; Multiple regression analysis; Muscles; Musculoskeletal system; nutrition; Obesity; Older people; Overweight; Plasma levels; Population; Population studies; Regression analysis; Skeletal muscle; standard deviation; Italy

Aging-associated skeletal muscle loss may be paralleled by increased fat mass, both contributing to frailty and related healthcare and social costs. In general population cohorts, unacylated ghrelin (UnAG) plasma levels, an emerging modulator of skeletal muscle metabolism with potential muscle-anabo...