Delayed Intracerebral Hemorrhage after Deep Brain Stimulation for Parkinson’s Disease

• Published in: Case reports in neurology Vol. 17; no. 1; pp. 62 - 71
• Main Authors: Chudy, Hana, Raguž, Marina, Marčinković, Petar, Rački, Valentino, Papić, Eliša, Hero, Mario, Vuletić, Vladimira, Chudy, Darko
• Format: Journal Article
• Language: English
• Published: Switzerland S. Karger AG 2025
• Subjects: Single Case – Neurosurgery; Subthalamic nucleus; Deep brain stimulation; Delayed ICH; Parkinson’s disease
• ISSN: 1662-680X; 1662-680X
• DOI: 10.1159/000546056

Introduction: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well-established treatment for advanced Parkinson’s disease (PD), offering significant symptomatic relief. Although DBS is generally considered safe, it carries risks, including the potential for delayed complications such as intracerebral hemorrhage (ICH). Case Presentation: We present a rare case of a 67-year-old male with PD who developed delayed ICH after undergoing bilateral STN DBS. Initially, the patient showed no neurological deficits postoperatively, with imaging confirming correct lead placement and no signs of hemorrhage. However, on the second postoperative day, the patient developed sudden right-sided hemiparesis. A CT scan revealed ICH alongside the left lead. The hemorrhage was managed conservatively, and the patient underwent extensive physical therapy, leading to significant improvement. Over the next 2 weeks, the patient’s condition improved, and follow-up CT scans showed complete resolution of the ICH. At this point, the left lead stimulation was initiated, further improving the patient’s PD symptoms. This case illustrates the potential for delayed ICH following STN DBS, emphasizing the need for ongoing monitoring and individualized treatment strategies. Conclusion: This case underscores the importance of vigilant postoperative monitoring and individualized management strategies in STN DBS patients. Early detection and appropriate management of complications such as ICH are crucial for minimizing risks and ensuring optimal patient outcomes. The potential for delayed complications highlights the need for continuous follow-up, even in the absence of immediate postoperative issues.