Ultrasound detection of lymphatic bubbles in a porcine dive model

• Published in: Journal of applied physiology (1985) Vol. 139; no. 2; pp. 365 - 375
• Main Authors: Currens, Joshua B., Moon, Richard E., Makowski, Matthew S., Natoli, Michael J., Leypoldt, Jayne, Woolard, Jean, Brown, David, Azarang, Arian, Brown, Robert, Schinazi, Eric, Ransom, Zach, Papadopoulou, Virginie, Lance, Rachel M.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.08.2025
• Subjects: Animal models; Animals; Biomarkers; Brightness; Bubbles; Decompression; Decompression - methods; Decompression sickness; Decompression Sickness - diagnostic imaging; Decompression Sickness - physiopathology; Disease Models, Animal; Dissection; Diving - physiology; Female; Lymph nodes; Lymph Nodes - diagnostic imaging; Lymphatic system; Male; Standardization; Streaming; Swine; Ultrasonic imaging; Ultrasonography - methods; Ultrasound; ultrasound imaging; decompression sickness; image quantification; lymphatics; physiological monitoring

This is the first ever study to noninvasively detect lymphatic decompression bubbles and examine their correspondence with severe decompression sickness (DCS) outcome. The image brightness analysis found that subjects with severe DCS were likely to have darker lymph node images postdive indicating p...