Enhanced echovirus 11 genomic surveillance in neonatal infections in Spain following a European alert reveals new recombinant forms linked to severe cases, 2019 to 2023

• Published in: Euro surveillance : bulletin européen sur les maladies transmissibles Vol. 29; no. 44; p. 1
• Main Authors: Fernandez-Garcia, Maria Dolores, Garcia-Ibañez, Nerea, Camacho, Juan, Gutierrez, Almudena, Sánchez García, Laura, Calvo, Cristina, Moreno-Docón, Antonio, Menasalvas, Ana Isabel, Medina, Antonio, Perez-Ruiz, Mercedes, Nieto Toboso, Maria Carmen, Muñoz-Almagro, Carmen, Launes, Cristian, Berengua, Carla, Cabrerizo, María
• Format: Journal Article
• Language: English
• Published: Sweden Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS) 31.10.2024; European Centre for Disease Prevention and Control (ECDC)
• Subjects: Adult; Child; Child, Preschool; Childrens health; Echovirus Infections - diagnosis; Echovirus Infections - epidemiology; Echovirus Infections - virology; Enterovirus B, Human - genetics; Enterovirus B, Human - isolation & purification; Female; Genome, Viral - genetics; Genomes; Genomics; Genotype; High-Throughput Nucleotide Sequencing; Humans; Infant; Infant, Newborn; Male; Neonatal care; Phylogeny; Spain - epidemiology; Surveillance; Spain; new variant; echovirus 11; recombinant; Enterovirus; neonatal infection; international alert; genomic surveillance

BackgroundIn 2023, a European alert was issued regarding an increase in severe enterovirus (EV) neonatal infections associated with echovirus 11 (E11) new lineage 1.AimTo analyse E11-positive cases between 2019 and 2023 to investigate whether the new lineage 1 circulated in Spain causing severe neon...