Haplotype Counting for Sensitive Chimerism Testing

• Published in: The Journal of molecular diagnostics : JMD Vol. 19; no. 3; pp. 427 - 436
• Main Authors: Debeljak, Marija, Mocci, Evelina, Morrison, Max C, Pallavajjalla, Aparna, Beierl, Katie, Amiel, Marie, Noë, Michaël, Wood, Laura D, Lin, Ming-Tseh, Gocke, Christopher D, Klein, Alison P, Fuchs, Ephraim J, Jones, Richard J, Eshleman, James R
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.05.2017
• Subjects: Pathology

Fields of forensics, transplantation, and paternity rely on human identity testing. Currently, this is accomplished through amplification of microsatellites followed by capillary electrophoresis. An alternative and theoretically better approach uses multiple single-nucleotide polymorphisms located w...