Are Perceived Stress and Cytokine Genotypes Clinically Feasible as Predictors of Psychoneuroimmune Symptoms in Advanced Cancer?

• Published in: Permanente journal Vol. 23; no. 3
• Main Authors: Gilbertson-White, Stephanie, Shahnazi, Ariana, Cherwin, Catherine
• Format: Journal Article
• Language: English
• Published: United States The Permanente Journal 2019
• Subjects: Case-Control Studies; Cytokines - genetics; Female; Genotype; Humans; Male; Middle Aged; Neoplasms - immunology; Neoplasms - psychology; Nursing Research & Practice; Polymorphism, Single Nucleotide; Predictive Value of Tests; Psychoneuroimmunology - methods; Severity of Illness Index; Stress, Psychological; Surveys and Questionnaires

Genetic variability and perceived stress have been identified as likely predictors of psychoneuroimmune (PNI) symptoms in patients with cancer. In the clinical setting, the ability to identify the patients at greatest risk of development of severe PNI symptoms continues to be elusive. To evaluate th...