Abnormal stimulated adherence of neonatal granulocytes: impaired induction of surface Mac-1 by chemotactic factors or secretagogues

• Published in: Blood Vol. 70; no. 3; pp. 740 - 750
• Main Authors: Anderson, DC, Freeman, KL, Heerdt, B, Hughes, BJ, Jack, RM, Smith, CW
• Format: Journal Article
• Language: English
• Published: 01.09.1987

To identify possible secretory determinants of impaired hyperadherence and stimulated migration of neonatal granulocytes (NGs), we performed correlative studies of: (a) specific granule content and exocytosis, (b) secretago-gue-mediated upregulation of f-met-leu-phe (fMLP) receptors, (c) the chemota...