Determination of the effect of silica nanoparticles on TRP currents in retinal pigment epithelial cells by entropy measurement

• Published in: Medical hypotheses Vol. 175; p. 111081
• Main Authors: Söğüt, Fatma, Akıllı, Mahmut, Kaynar, Ayşe Hümeyra, Tuncel, Handan, Kibar, Deniz, Yılmaz, Şakir Necat, Çömelekoglu, Ülkü
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.06.2023
• Subjects: Entropy; Ion channel; Nanoparticle; Retinal pigment epithelium; TRP channel; Whole cell recording; TRP channel; Whole cell recording; Entropy; Ion channel; Nanoparticle; Retinal pigment epithelium

Ion channels in cell membranes are gated, water-filled pores that allow passive transport of ions across the membrane along their electrochemical gradient. Recent studies have shown that nanoparticles can interact with ion channels and change their currents kinetics properties of the channel. In thi...