Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors

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Published inGene reports Vol. 10; pp. 17 - 25
Main Authors Dikhit, Manas R., Ansari, Md Yousuf, sinha, Sahil, Ali, Vahab, Topno, Roshan Kamal, Majhee, Jyoti Prava, Sahoo, Ganesh C., Das, Pradeep
Format Journal Article
LanguageEnglish
Published 01.03.2018
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Author Sahoo, Ganesh C.
Topno, Roshan Kamal
Ansari, Md Yousuf
Ali, Vahab
sinha, Sahil
Das, Pradeep
Dikhit, Manas R.
Majhee, Jyoti Prava
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Cites_doi 10.1039/C3MB70600A
10.2174/15701808113109990070
10.1016/S1201-9712(00)90078-X
10.1042/bse0510063
10.1128/AAC.48.8.3033-3042.2004
10.1007/s00894-010-0649-0
10.1016/j.pt.2005.07.001
10.1093/nar/gkm290
10.1016/S0021-9258(17)35237-7
10.1016/j.meegid.2016.08.037
10.1086/314896
10.1155/2013/185282
10.1016/S0925-4439(02)00088-1
10.1021/bi00421a006
10.1007/s00894-009-0565-3
10.1016/j.ijbiomac.2012.01.010
10.1504/IJBRA.2014.060761
10.1074/jbc.270.29.17204
10.1186/1475-2875-9-351
10.1080/1062936X.2013.765912
10.4269/ajtmh.1992.47.117
10.1002/jcc.20291
10.1016/S0076-6879(97)77022-8
10.1128/AAC.02429-16
10.1016/j.molbiopara.2009.06.011
10.1080/07391102.2015.1134349
10.3201/eid1602.090623
10.1111/pim.12451
10.1128/AAC.49.8.3234-3238.2005
10.1007/s00726-014-1872-2
10.1038/nrmicro1748
10.1093/nar/gkh398
10.1016/j.micinf.2017.03.002
10.1104/pp.81.2.553
10.1016/j.genrep.2017.09.003
10.1002/prot.22499
10.1128/AAC.02834-14
10.1002/elps.1150181505
10.1016/j.molimm.2016.12.022
10.1074/jbc.M708014200
10.1128/CMR.14.3.659-688.2001
10.1093/bioinformatics/18.9.1250
10.1016/j.meegid.2015.10.012
10.1080/07391102.2013.789400
10.1016/j.ijbiomac.2015.11.051
10.1186/1475-2875-11-194
10.1074/jbc.M111976200
10.1128/MCB.00344-16
10.1016/j.pep.2006.10.013
10.1128/AAC.41.4.827
10.1016/j.ijpara.2014.08.013
10.1038/nsb921
10.1016/j.jmb.2004.05.028
10.1155/2013/609289
10.1080/07391102.2012.698189
10.1086/318121
10.1002/andp.19213690304
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References Chandra Sahoo (10.1016/j.genrep.2017.10.010_bb0065) 2014; 11
Bendtsen (10.1016/j.genrep.2017.10.010_bb0050) 2004; 340
Yuvaniyama (10.1016/j.genrep.2017.10.010_bb0320) 2003; 10
Eisenberg (10.1016/j.genrep.2017.10.010_bb0110) 1997; 277
Davis (10.1016/j.genrep.2017.10.010_bb0075) 2004; 32
Hildebrand (10.1016/j.genrep.2017.10.010_bb0155) 2009; 77
Murray (10.1016/j.genrep.2017.10.010_bb0200) 2000; 4
Read (10.1016/j.genrep.2017.10.010_bb0215) 2010; 9
Vickers (10.1016/j.genrep.2017.10.010_bb0300) 2011; 51
Kar (10.1016/j.genrep.2017.10.010_bb0165) 2013; 24
Amit (10.1016/j.genrep.2017.10.010_bb0010) 2017; 82
Herwaldt (10.1016/j.genrep.2017.10.010_bb0150) 2001; 14
Vatsyayan (10.1016/j.genrep.2017.10.010_bb0295) 2007; 52
Faraut-Gambarelli (10.1016/j.genrep.2017.10.010_bb0125) 1997; 41
Sahoo (10.1016/j.genrep.2017.10.010_bb0225) 2013; 31
Webb (10.1016/j.genrep.2017.10.010_bb0305) 1995; 270
Pang (10.1016/j.genrep.2017.10.010_bb0205) 2009; 168
Dikhit (10.1016/j.genrep.2017.10.010_bb0085) 2016; 10
Kumar (10.1016/j.genrep.2017.10.010_bb0170) 2014; 58
Ansari (10.1016/j.genrep.2017.10.010_bb0035) 2017; 9
Dikhit (10.1016/j.genrep.2017.10.010_bb0080) 2015; 36
Kar (10.1016/j.genrep.2017.10.010_bb0160) 2013; 6092
Salcedo (10.1016/j.genrep.2017.10.010_bb0250) 2005; 21
Grogl (10.1016/j.genrep.2017.10.010_bb0140) 1992; 47
Chappuis (10.1016/j.genrep.2017.10.010_bb0070) 2007; 5
Sahoo (10.1016/j.genrep.2017.10.010_bb0220) 2013; 2013
Sahoo (10.1016/j.genrep.2017.10.010_bb0245) 2015; 47
Sahoo (10.1016/j.genrep.2017.10.010_bb0230) 2014; 32
Sahoo (10.1016/j.genrep.2017.10.010_bb0235) 2014; 10
Guex (10.1016/j.genrep.2017.10.010_bb0145) 1997; 18
Amit (10.1016/j.genrep.2017.10.010_bb0015) 2017; 35
Gilbert (10.1016/j.genrep.2017.10.010_bb0130) 2002; 1587
Sahoo (10.1016/j.genrep.2017.10.010_bb0240) 2014; 10
Senkovich (10.1016/j.genrep.2017.10.010_bb0265) 2005; 49
Sundar (10.1016/j.genrep.2017.10.010_bb0280) 2000; 31
Trivedi (10.1016/j.genrep.2017.10.010_bb0285) 2002; 277
Rani (10.1016/j.genrep.2017.10.010_bb0210) 2016; 17
Van Der Spoel (10.1016/j.genrep.2017.10.010_bb0290) 2005; 26
Sopitthummakhun (10.1016/j.genrep.2017.10.010_bb0275) 2012; 11
Yadav (10.1016/j.genrep.2017.10.010_bb0315) 2015; 45
Shostak (10.1016/j.genrep.2017.10.010_bb0270) 1988; 27
Lambert (10.1016/j.genrep.2017.10.010_bb0175) 2002; 18
Dikhit (10.1016/j.genrep.2017.10.010_bb0095) 2016; 10
Maganti (10.1016/j.genrep.2017.10.010_bb0185) 2010; 16
Dikhit (10.1016/j.genrep.2017.10.010_bb0105) 2017
Abhishek (10.1016/j.genrep.2017.10.010_bb0005) 2017; 37
Dikhit (10.1016/j.genrep.2017.10.010_bb0100) 2017; 39
Lira (10.1016/j.genrep.2017.10.010_bb0180) 1999; 180
Grant (10.1016/j.genrep.2017.10.010_bb0135) 2004; 48
Ansari (10.1016/j.genrep.2017.10.010_bb0040) 2017; 8
Eswar (10.1016/j.genrep.2017.10.010_bb0115) 2008
Amit (10.1016/j.genrep.2017.10.010_bb0020) 2017; 19
Mitchell (10.1016/j.genrep.2017.10.010_bb0195) 1986; 81
Mansuri (10.1016/j.genrep.2017.10.010_bb0190) 2017; 61
Dikhit (10.1016/j.genrep.2017.10.010_bb0090) 2016; 45
Ansari (10.1016/j.genrep.2017.10.010_bb0025) 2012; 50
Ewald (10.1016/j.genrep.2017.10.010_bb0120) 1921; 369
Schirch (10.1016/j.genrep.2017.10.010_bb0255) 1991; 266
Bhattarai (10.1016/j.genrep.2017.10.010_bb0055) 2010; 16
Scott (10.1016/j.genrep.2017.10.010_bb0260) 2008; 283
Awale (10.1016/j.genrep.2017.10.010_bb0045) 2010; 16
Capelluto (10.1016/j.genrep.2017.10.010_bb0060) 2000; 267
Ansari (10.1016/j.genrep.2017.10.010_bb0030) 2016; 83
Wiederstein (10.1016/j.genrep.2017.10.010_bb0310) 2007; 35
References_xml – volume: 10
  start-page: 1104
  year: 2014
  ident: 10.1016/j.genrep.2017.10.010_bb0235
  article-title: A conformational analysis of mouse Nalp3 domain structures by molecular dynamics simulations, and binding site analysis
  publication-title: Mol. BioSyst.
  doi: 10.1039/C3MB70600A
  contributor:
    fullname: Sahoo
– volume: 11
  start-page: 211
  year: 2014
  ident: 10.1016/j.genrep.2017.10.010_bb0065
  article-title: Molecular modeling and ligand-protein interaction of N-protein of Chandipura virus
  publication-title: Lett. Drug Des. Discovery
  doi: 10.2174/15701808113109990070
  contributor:
    fullname: Chandra Sahoo
– volume: 267
  start-page: 712
  year: 2000
  ident: 10.1016/j.genrep.2017.10.010_bb0060
  article-title: Purification and some properties of serine hydroxymethyltransferase from Trypanosoma cruzi
  publication-title: FEBS J.
  contributor:
    fullname: Capelluto
– volume: 10
  start-page: 1753
  year: 2016
  ident: 10.1016/j.genrep.2017.10.010_bb0095
  article-title: Activity of a novel sulfonamide compound 2-nitro-N-(pyridin-2-ylmethyl)benzenesulfonamide against Leishmania donovani
  publication-title: Drug Des. Devel. Ther.
  contributor:
    fullname: Dikhit
– volume: 4
  start-page: 158
  year: 2000
  ident: 10.1016/j.genrep.2017.10.010_bb0200
  article-title: Treatment of visceral leishmaniasis (kala-azar): a decade of progress and future approaches
  publication-title: Int. J. Infect. Dis.
  doi: 10.1016/S1201-9712(00)90078-X
  contributor:
    fullname: Murray
– volume: 51
  start-page: 63
  year: 2011
  ident: 10.1016/j.genrep.2017.10.010_bb0300
  article-title: Folate metabolic pathways in Leishmania
  publication-title: Essays Biochem.
  doi: 10.1042/bse0510063
  contributor:
    fullname: Vickers
– volume: 48
  start-page: 3033
  year: 2004
  ident: 10.1016/j.genrep.2017.10.010_bb0135
  article-title: Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/AAC.48.8.3033-3042.2004
  contributor:
    fullname: Grant
– volume: 16
  start-page: 1539
  year: 2010
  ident: 10.1016/j.genrep.2017.10.010_bb0185
  article-title: Probing the structure of Leishmania donovani chagasi DHFR-TS: comparative protein modeling and protein–ligand interaction studies
  publication-title: J. Mol. Model.
  doi: 10.1007/s00894-010-0649-0
  contributor:
    fullname: Maganti
– volume: 21
  start-page: 406
  year: 2005
  ident: 10.1016/j.genrep.2017.10.010_bb0250
  article-title: A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum
  publication-title: Trends Parasitol.
  doi: 10.1016/j.pt.2005.07.001
  contributor:
    fullname: Salcedo
– volume: 35
  start-page: W407
  year: 2007
  ident: 10.1016/j.genrep.2017.10.010_bb0310
  article-title: ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkm290
  contributor:
    fullname: Wiederstein
– volume: 266
  start-page: 759
  year: 1991
  ident: 10.1016/j.genrep.2017.10.010_bb0255
  article-title: The origin of reaction specificity in serine hydroxymethyltransferase
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(17)35237-7
  contributor:
    fullname: Schirch
– volume: 45
  start-page: 187
  year: 2016
  ident: 10.1016/j.genrep.2017.10.010_bb0090
  article-title: Computational prediction and analysis of potential antigenic CTL epitopes in Zika virus: a first step towards vaccine development
  publication-title: Infect. Genet. Evol.
  doi: 10.1016/j.meegid.2016.08.037
  contributor:
    fullname: Dikhit
– volume: 180
  start-page: 564
  year: 1999
  ident: 10.1016/j.genrep.2017.10.010_bb0180
  article-title: Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
  publication-title: J Infect Dis
  doi: 10.1086/314896
  contributor:
    fullname: Lira
– volume: 2013
  year: 2013
  ident: 10.1016/j.genrep.2017.10.010_bb0220
  article-title: Elucidation of novel structural scaffold in rohu TLR2 and its binding site analysis with peptidoglycan, lipoteichoic acid and zymosan ligands, and downstream MyD88 adaptor protein
  publication-title: Biomed. Res. Int.
  doi: 10.1155/2013/185282
  contributor:
    fullname: Sahoo
– volume: 1587
  start-page: 249
  year: 2002
  ident: 10.1016/j.genrep.2017.10.010_bb0130
  article-title: Inhibitors of dihydrofolate reductase in Leishmania and trypanosomes
  publication-title: Biochim. Biophys. Acta (BBA) - Mol. Basis Dis.
  doi: 10.1016/S0925-4439(02)00088-1
  contributor:
    fullname: Gilbert
– volume: 27
  start-page: 8007
  year: 1988
  ident: 10.1016/j.genrep.2017.10.010_bb0270
  article-title: Serine hydroxymethyltransferase: mechanism of the racemization and transamination of D-and L-alanine
  publication-title: Biochemistry
  doi: 10.1021/bi00421a006
  contributor:
    fullname: Shostak
– volume: 16
  start-page: 475
  year: 2010
  ident: 10.1016/j.genrep.2017.10.010_bb0045
  article-title: Homology modeling and atomic level binding study of Leishmania MAPK with inhibitors
  publication-title: J. Mol. Model.
  doi: 10.1007/s00894-009-0565-3
  contributor:
    fullname: Awale
– volume: 50
  start-page: 637
  year: 2012
  ident: 10.1016/j.genrep.2017.10.010_bb0025
  article-title: Comparative modeling of HGPRT enzyme of L. Donovani and binding affinities of different analogs of GMP
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2012.01.010
  contributor:
    fullname: Ansari
– volume: 10
  start-page: 235
  year: 2014
  ident: 10.1016/j.genrep.2017.10.010_bb0240
  article-title: Structure, evolution and virtual screening of NDM-1 strain from Kolkata
  publication-title: Int. J. Bioinforma. Res. Appl.
  doi: 10.1504/IJBRA.2014.060761
  contributor:
    fullname: Sahoo
– volume: 270
  start-page: 17204
  year: 1995
  ident: 10.1016/j.genrep.2017.10.010_bb0305
  article-title: 4-Chlorothreonine is substrate, mechanistic probe, and mechanism-based inactivator of serine hydroxymethyltransferase
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.270.29.17204
  contributor:
    fullname: Webb
– volume: 9
  start-page: 351
  year: 2010
  ident: 10.1016/j.genrep.2017.10.010_bb0215
  article-title: Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum
  publication-title: Malar. J.
  doi: 10.1186/1475-2875-9-351
  contributor:
    fullname: Read
– start-page: 145
  year: 2008
  ident: 10.1016/j.genrep.2017.10.010_bb0115
  article-title: Protein structure modeling with MODELLER
  contributor:
    fullname: Eswar
– volume: 24
  start-page: 215
  year: 2013
  ident: 10.1016/j.genrep.2017.10.010_bb0165
  article-title: Exploring novel KDR inhibitors based on pharmaco-informatics methodology
  publication-title: SAR QSAR Environ. Res.
  doi: 10.1080/1062936X.2013.765912
  contributor:
    fullname: Kar
– volume: 17
  year: 2016
  ident: 10.1016/j.genrep.2017.10.010_bb0210
  article-title: Computational elucidation of structural basis for ligand binding with mycobacterium tuberculosis Glucose-1-phosphate Thymidylyltransferase (RmlA)
  publication-title: Curr. Pharm. Biotechnol.
  contributor:
    fullname: Rani
– volume: 47
  start-page: 117
  year: 1992
  ident: 10.1016/j.genrep.2017.10.010_bb0140
  article-title: Drug resistance in leishmaniasis: its implication in systemic chemotherapy of cutaneous and mucocutaneous disease
  publication-title: Am. J. Trop. Med. Hyg.
  doi: 10.4269/ajtmh.1992.47.117
  contributor:
    fullname: Grogl
– volume: 26
  start-page: 1701
  year: 2005
  ident: 10.1016/j.genrep.2017.10.010_bb0290
  article-title: GROMACS: fast, flexible, and free
  publication-title: J. Comput. Chem.
  doi: 10.1002/jcc.20291
  contributor:
    fullname: Van Der Spoel
– volume: 277
  start-page: 396
  year: 1997
  ident: 10.1016/j.genrep.2017.10.010_bb0110
  article-title: [20] VERIFY3D: assessment of protein models with three-dimensional profiles
  publication-title: Methods Enzymol.
  doi: 10.1016/S0076-6879(97)77022-8
  contributor:
    fullname: Eisenberg
– volume: 61
  issue: 7
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0190
  article-title: In vitro evaluation of antileishmanial activity of computationally screened compounds against ascorbate peroxidase: combating amphotericin b drug resistance
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/AAC.02429-16
  contributor:
    fullname: Mansuri
– volume: 168
  start-page: 74
  year: 2009
  ident: 10.1016/j.genrep.2017.10.010_bb0205
  article-title: Catalytic and ligand-binding characteristics of plasmodium falciparum serine hydroxymethyltransferase
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/j.molbiopara.2009.06.011
  contributor:
    fullname: Pang
– volume: 35
  start-page: 128
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0015
  article-title: Immunomodulation mediated through Leishmania donovani protein disulfide isomerase by eliciting CD8+ T-cell in cured visceral leishmaniasis subjects and identification of its possible HLA class-1 restricted T-cell epitopes
  publication-title: J. Biomol. Struct. Dyn.
  doi: 10.1080/07391102.2015.1134349
  contributor:
    fullname: Amit
– volume: 16
  start-page: 231
  year: 2010
  ident: 10.1016/j.genrep.2017.10.010_bb0055
  article-title: Domestic animals and epidemiology of visceral leishmaniasis, Nepal
  publication-title: Emerg. Infect. Dis.
  doi: 10.3201/eid1602.090623
  contributor:
    fullname: Bhattarai
– volume: 39
  start-page: e12451
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0100
  article-title: Vaccine potential of HLA A2 epitopes from Leishmania cysteine protease type III (CPC)
  publication-title: Parasite Immunol.
  doi: 10.1111/pim.12451
  contributor:
    fullname: Dikhit
– volume: 49
  start-page: 3234
  year: 2005
  ident: 10.1016/j.genrep.2017.10.010_bb0265
  article-title: Lipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/AAC.49.8.3234-3238.2005
  contributor:
    fullname: Senkovich
– volume: 47
  start-page: 381
  year: 2015
  ident: 10.1016/j.genrep.2017.10.010_bb0245
  article-title: Understanding the distinguishable structural and functional features in zebrafish TLR3 and TLR22, and their binding modes with fish dsRNA viruses: an exploratory structural model analysis
  publication-title: Amino Acids
  doi: 10.1007/s00726-014-1872-2
  contributor:
    fullname: Sahoo
– volume: 5
  start-page: 873
  year: 2007
  ident: 10.1016/j.genrep.2017.10.010_bb0070
  article-title: Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro1748
  contributor:
    fullname: Chappuis
– volume: 32
  start-page: W615
  year: 2004
  ident: 10.1016/j.genrep.2017.10.010_bb0075
  article-title: MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkh398
  contributor:
    fullname: Davis
– volume: 19
  start-page: 358
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0020
  article-title: Immuno-informatics based approaches to identify CD8+ T cell epitopes within the Leishmania donovani 3-ectonucleotidase in cured visceral leishmaniasis subjects
  publication-title: Microbes Infect.
  doi: 10.1016/j.micinf.2017.03.002
  contributor:
    fullname: Amit
– volume: 81
  start-page: 553
  year: 1986
  ident: 10.1016/j.genrep.2017.10.010_bb0195
  article-title: Serine Hydroxymethyltransferase from soybean root nodules purification and kinetic properties
  publication-title: Plant Physiol.
  doi: 10.1104/pp.81.2.553
  contributor:
    fullname: Mitchell
– volume: 9
  start-page: 86
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0035
  article-title: Recent advancement and treatment of leishmaniasis based on pharmacoinformatics approach: current and future outlook
  publication-title: Gene Reports
  doi: 10.1016/j.genrep.2017.09.003
  contributor:
    fullname: Ansari
– volume: 77
  start-page: 128
  issue: Suppl. 9
  year: 2009
  ident: 10.1016/j.genrep.2017.10.010_bb0155
  article-title: Fast and accurate automatic structure prediction with HHpred
  publication-title: Proteins
  doi: 10.1002/prot.22499
  contributor:
    fullname: Hildebrand
– volume: 58
  start-page: 6172
  year: 2014
  ident: 10.1016/j.genrep.2017.10.010_bb0170
  article-title: Ascorbate peroxidase, a key molecule regulating amphotericin B resistance in clinical isolates of Leishmania donovani
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/AAC.02834-14
  contributor:
    fullname: Kumar
– volume: 18
  start-page: 2714
  year: 1997
  ident: 10.1016/j.genrep.2017.10.010_bb0145
  article-title: SWISS-MODEL and the Swiss-Pdb viewer: an environment for comparative protein modeling
  publication-title: Electrophoresis
  doi: 10.1002/elps.1150181505
  contributor:
    fullname: Guex
– volume: 82
  start-page: 104
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0010
  article-title: Immunization with Leishmania donovani protein disulfide isomerase DNA construct induces Th1 and Th17 dependent immune response and protection against experimental visceral leishmaniasis in Balb/c mice
  publication-title: Mol. Immunol.
  doi: 10.1016/j.molimm.2016.12.022
  contributor:
    fullname: Amit
– volume: 283
  start-page: 155
  year: 2008
  ident: 10.1016/j.genrep.2017.10.010_bb0260
  article-title: The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M708014200
  contributor:
    fullname: Scott
– volume: 14
  start-page: 659
  year: 2001
  ident: 10.1016/j.genrep.2017.10.010_bb0150
  article-title: Laboratory-acquired parasitic infections from accidental exposures
  publication-title: Clin. Microbiol. Rev.
  doi: 10.1128/CMR.14.3.659-688.2001
  contributor:
    fullname: Herwaldt
– volume: 18
  start-page: 1250
  year: 2002
  ident: 10.1016/j.genrep.2017.10.010_bb0175
  article-title: ESyPred3D: prediction of proteins 3D structures
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/18.9.1250
  contributor:
    fullname: Lambert
– year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0105
  article-title: Mining the Proteome of Leishmania donovani for the Development of Novel MHC Class I Restricted Epitope for the Control of Visceral Leishmaniasis
  publication-title: J. Cell. Biochem.
  contributor:
    fullname: Dikhit
– volume: 36
  start-page: 369
  year: 2015
  ident: 10.1016/j.genrep.2017.10.010_bb0080
  article-title: Computational elucidation of potential antigenic CTL epitopes in Ebola virus
  publication-title: Infect. Genet. Evol.
  doi: 10.1016/j.meegid.2015.10.012
  contributor:
    fullname: Dikhit
– volume: 32
  start-page: 709
  year: 2014
  ident: 10.1016/j.genrep.2017.10.010_bb0230
  article-title: Structure prediction of gBP21 protein of L. donovani and its molecular interaction
  publication-title: J. Biomol. Struct. Dyn.
  doi: 10.1080/07391102.2013.789400
  contributor:
    fullname: Sahoo
– volume: 83
  start-page: 78
  year: 2016
  ident: 10.1016/j.genrep.2017.10.010_bb0030
  article-title: Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2015.11.051
  contributor:
    fullname: Ansari
– volume: 11
  start-page: 194
  year: 2012
  ident: 10.1016/j.genrep.2017.10.010_bb0275
  article-title: Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay
  publication-title: Malar. J.
  doi: 10.1186/1475-2875-11-194
  contributor:
    fullname: Sopitthummakhun
– volume: 277
  start-page: 17161
  year: 2002
  ident: 10.1016/j.genrep.2017.10.010_bb0285
  article-title: Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus Stearothermophilus insights into the catalytic mechanism
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M111976200
  contributor:
    fullname: Trivedi
– volume: 37
  start-page: e00344
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0005
  article-title: Phosphorylation of translation initiation factor 2-alpha in Leishmania donovani under stress is necessary for parasite survival
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.00344-16
  contributor:
    fullname: Abhishek
– volume: 10
  start-page: 1753
  year: 2016
  ident: 10.1016/j.genrep.2017.10.010_bb0085
  article-title: Activity of a novel sulfonamide compound 2-nitro-N-(pyridin-2-ylmethyl) benzenesulfonamide against Leishmania donovani
  publication-title: Drug Des. Devel. Ther.
  contributor:
    fullname: Dikhit
– volume: 52
  start-page: 433
  year: 2007
  ident: 10.1016/j.genrep.2017.10.010_bb0295
  article-title: Molecular cloning and biochemical characterization of Leishmania donovani serine hydroxymethyltransferase
  publication-title: Protein Expr. Purif.
  doi: 10.1016/j.pep.2006.10.013
  contributor:
    fullname: Vatsyayan
– volume: 41
  start-page: 827
  year: 1997
  ident: 10.1016/j.genrep.2017.10.010_bb0125
  article-title: In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/AAC.41.4.827
  contributor:
    fullname: Faraut-Gambarelli
– volume: 8
  start-page: 134
  year: 2017
  ident: 10.1016/j.genrep.2017.10.010_bb0040
  article-title: In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors
  contributor:
    fullname: Ansari
– volume: 45
  start-page: 33
  year: 2015
  ident: 10.1016/j.genrep.2017.10.010_bb0315
  article-title: Leishmania donovani: impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2014.08.013
  contributor:
    fullname: Yadav
– volume: 10
  start-page: 357
  year: 2003
  ident: 10.1016/j.genrep.2017.10.010_bb0320
  article-title: Insights into antifolate resistance from malarial DHFR-TS structures
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsb921
  contributor:
    fullname: Yuvaniyama
– volume: 340
  start-page: 783
  year: 2004
  ident: 10.1016/j.genrep.2017.10.010_bb0050
  article-title: Improved prediction of signal peptides: SignalP 3.0
  publication-title: J. Mol. Biol.
  doi: 10.1016/j.jmb.2004.05.028
  contributor:
    fullname: Bendtsen
– volume: 6092
  start-page: 1
  year: 2013
  ident: 10.1016/j.genrep.2017.10.010_bb0160
  article-title: Computational elucidation of structural basis for ligand binding with Leishmania donovani adenosine kinase
  publication-title: Biomed. Res. Int.
  doi: 10.1155/2013/609289
  contributor:
    fullname: Kar
– volume: 31
  start-page: 258
  year: 2013
  ident: 10.1016/j.genrep.2017.10.010_bb0225
  article-title: Analysis of sequence, structure of GAPDH of Leishmania donovani and its interactions
  publication-title: J. Biomol. Struct. Dyn.
  doi: 10.1080/07391102.2012.698189
  contributor:
    fullname: Sahoo
– volume: 31
  start-page: 1104
  year: 2000
  ident: 10.1016/j.genrep.2017.10.010_bb0280
  article-title: Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic
  publication-title: Clin. Infect. Dis.
  doi: 10.1086/318121
  contributor:
    fullname: Sundar
– volume: 369
  start-page: 253
  year: 1921
  ident: 10.1016/j.genrep.2017.10.010_bb0120
  article-title: Die Berechnung optischer und elektrostatischer Gitterpotentiale
  publication-title: Ann. Phys.
  doi: 10.1002/andp.19213690304
  contributor:
    fullname: Ewald
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