Impact of sarcosine on diabetic retinopathy: Findings based on weighted gene co‐expression network analysis and machine learning techniques

• Published in: Diabetes, obesity & metabolism Vol. 25; no. 12; pp. 3501 - 3511
• Main Authors: Che, Mingzhu, Xia, Zhezheng, Jiang, Depeng, Wang, Yanan, Wang, Hui, Chen, Yuxin, Wang, Ziyi, Chen, Yang, Zhang, Xinlv, Zhang, Zejie, Guo, Chengnan, Zhang, Xiaoyu, Zheng, Chao, Mao, Guangyun
• Format: Journal Article
• Language: English
• Published: Oxford Wiley Subscription Services, Inc 01.12.2023
• Subjects: Body mass index; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetic retinopathy; Genomes; High density lipoprotein; Metabolites; Regression analysis; Retinopathy; Sarcosine

AimTo quantify the association between serum sarcosine and diabetic retinopathy (DR) using weighted gene co‐expression network analysis (WGCNA).MethodsWe measured serum metabolites in 69 pairs of type 2 diabetes (T2D) patients with and without DR matched by age, gender, body mass index（BMI and HbA1c...