Synthesis and biological evaluation of aryl amide derivatives of pyridine-imidazo[1,2-a]pyrazine-oxazole as anticancer agents

• Published in: Chemical Data Collections Vol. 55; p. 101176
• Main Authors: Vanam, Narendhar Reddy, Gadipelli, Prakash, Anireddy, Jaya Shree
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2025
• Subjects: 1,3-oxazole and anticancer activity; Coelenterazine; Imidazo[1,2-a]pyrazine; Mubritinib; Mubritinib; Imidazo[1,2-a]pyrazine; Coelenterazine; 1,3-oxazole and anticancer activity

A new series of aryl amide derivatives of pyridine-imidazo[1,2-a]pyrazine-oxazoles (15a-j) has been designed, synthesized and screened for their anticancer activity against MCF-7 (human breast cancer), A549 (human lung cancer), Colo-205 (human colon cancer) and A2780 (human ovarian cancer) cell line...