Effects on radiation oncology treatments involving various neuromodulation devices
Where no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for neurosurgeons and radiation oncologists who rely on the computerized treatment plan clinically for cancer patients. The focus of the article is to ch...
Saved in:
Published in | Journal of X-ray science and technology Vol. 19; no. 4; pp. 443 - 456 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
2011
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Where no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for neurosurgeons and radiation oncologists who rely on the computerized treatment plan clinically for cancer patients. The focus of the article is to characterize radiation parameters of attenuation and scatter when an incident therapeutic x-ray beam is directed upon them. At the time of this writing, manufacturers of Neuromodulation products do not recommend direct exposure of the device in the beam nor provide guidance for the maximum dose for these devices.
Ten neuromodulation models were chosen to represent the finite class of devices marketed by Medtronic before 2011. CT simulations permitted computer treatment modeling for dose distribution analysis as used routinely in radiation oncology for patients. Phantom case results were directly compared to actual clinical patient cases. Radiation detection measurements were then correlated to computational results. Where the x-ray beam passes through the device and is attenuated, dose reduction was identified with Varian Eclipse computer modeling for these posterior locations.
Although the computer algorithm did not identify physical processes of side-scatter and back-scatter, these phenomena were proven by radiation measurement to occur. In general, the computer results underestimated the level of change seen by measurement.
For these implantable neurostimulators, the spread in dose changes were found to be -6.2% to -12.5% by attenuation, +1.7% to +3.8% by side-scatter, and +1.1% to +3.1% by back-scatter at 6 MV. At 18 MV, these findings were observed to be -1.4% to -7.0% by attenuation, +1.8% to 5.7% by side-scatter, and 0.8% to 2.7% by back-scatter. No pattern for the behavior of these phenomena was deduced to be a direct consequence of device size. |
---|---|
AbstractList | OBJECTWhere no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for neurosurgeons and radiation oncologists who rely on the computerized treatment plan clinically for cancer patients. The focus of the article is to characterize radiation parameters of attenuation and scatter when an incident therapeutic x-ray beam is directed upon them. At the time of this writing, manufacturers of Neuromodulation products do not recommend direct exposure of the device in the beam nor provide guidance for the maximum dose for these devices.METHODSTen neuromodulation models were chosen to represent the finite class of devices marketed by Medtronic before 2011. CT simulations permitted computer treatment modeling for dose distribution analysis as used routinely in radiation oncology for patients. Phantom case results were directly compared to actual clinical patient cases. Radiation detection measurements were then correlated to computational results. Where the x-ray beam passes through the device and is attenuated, dose reduction was identified with Varian Eclipse computer modeling for these posterior locations.RESULTSAlthough the computer algorithm did not identify physical processes of side-scatter and back-scatter, these phenomena were proven by radiation measurement to occur. In general, the computer results underestimated the level of change seen by measurement.CONCLUSIONSFor these implantable neurostimulators, the spread in dose changes were found to be -6.2% to -12.5% by attenuation, +1.7% to +3.8% by side-scatter, and +1.1% to +3.1% by back-scatter at 6 MV. At 18 MV, these findings were observed to be -1.4% to -7.0% by attenuation, +1.8% to 5.7% by side-scatter, and 0.8% to 2.7% by back-scatter. No pattern for the behavior of these phenomena was deduced to be a direct consequence of device size. Where no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for neurosurgeons and radiation oncologists who rely on the computerized treatment plan clinically for cancer patients. The focus of the article is to characterize radiation parameters of attenuation and scatter when an incident therapeutic x-ray beam is directed upon them. At the time of this writing, manufacturers of Neuromodulation products do not recommend direct exposure of the device in the beam nor provide guidance for the maximum dose for these devices. Ten neuromodulation models were chosen to represent the finite class of devices marketed by Medtronic before 2011. CT simulations permitted computer treatment modeling for dose distribution analysis as used routinely in radiation oncology for patients. Phantom case results were directly compared to actual clinical patient cases. Radiation detection measurements were then correlated to computational results. Where the x-ray beam passes through the device and is attenuated, dose reduction was identified with Varian Eclipse computer modeling for these posterior locations. Although the computer algorithm did not identify physical processes of side-scatter and back-scatter, these phenomena were proven by radiation measurement to occur. In general, the computer results underestimated the level of change seen by measurement. For these implantable neurostimulators, the spread in dose changes were found to be -6.2% to -12.5% by attenuation, +1.7% to +3.8% by side-scatter, and +1.1% to +3.1% by back-scatter at 6 MV. At 18 MV, these findings were observed to be -1.4% to -7.0% by attenuation, +1.8% to 5.7% by side-scatter, and 0.8% to 2.7% by back-scatter. No pattern for the behavior of these phenomena was deduced to be a direct consequence of device size. |
Author | Paralikar, Kunal J Wilkinson, Jeffrey D Lawson, Raymond C Gossman, Michael S Hebb, Adam O Lopez, Jeffrey P Powell, James S Graves-Calhoun, Alison R |
Author_xml | – sequence: 1 givenname: Michael S surname: Gossman fullname: Gossman, Michael S organization: Radiation Oncology Department, Tri-State Regional Cancer Center, Ashland, KY, USA – sequence: 2 givenname: Kunal J surname: Paralikar fullname: Paralikar, Kunal J organization: Neuromodulation Product Development and Technology RSE, Medtronic, Inc., Minneapolis, MN, USA – sequence: 3 givenname: Adam O surname: Hebb fullname: Hebb, Adam O organization: Department of Neurological Surgery, University of Washington, Seattle, WA, USA – sequence: 4 givenname: Jeffrey D surname: Wilkinson fullname: Wilkinson, Jeffrey D organization: Rhythm Disease Management Division, External Research Program, Medtronic, Inc., Mounds View, MN, USA – sequence: 5 givenname: Alison R surname: Graves-Calhoun fullname: Graves-Calhoun, Alison R organization: Rhythm Disease Management Division, External Research Program, Medtronic, Inc., Mounds View, MN, USA – sequence: 6 givenname: Raymond C surname: Lawson fullname: Lawson, Raymond C organization: Radiation Oncology Department, Tri-State Regional Cancer Center, Ashland, KY, USA – sequence: 7 givenname: Jeffrey P surname: Lopez fullname: Lopez, Jeffrey P organization: Radiation Oncology Department, Ashland Radiation Oncology, Ashland, KY, USA – sequence: 8 givenname: James S surname: Powell fullname: Powell, James S organization: Tri-State Christian Neurosurgical Associates, Ashland, KY, USA |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25214379$$D View this record in MEDLINE/PubMed |
BookMark | eNo9kEtLAzEUhYNUbK0u3cos3YwmufNIllLqAwqCVnAXMjN3SmQmqclMof_elFZX9yy-c7h8l2RinUVCbhi9Bw7w8PWxTjllLKVAizMyY1TmqWQsm5AZFTGDlMWUXIbwTSOWC3FBpjznLINSzsj7sm2xHkLibOJ1Y_RgYnK2dp3b7JPBox56tBEwdue6nbGbZKe9cWNILI7e9a4Zu2OrwZ2pMVyR81Z3Aa9Pd04-n5brxUu6ent-XTyu0ppnckgrwAYqjkUhhQChSyg5Z4B5AZlAyssmb1pK2wwKxnlDKQXIKtAoRSVamcGc3B13t979jBgG1ZtQY9dpi_E9xfKCyRLykkY0PaK1dyF4bNXWm177vWJUHTSqqFEdNKqDxsjfnqbHqsfmn_7zBr8NXG-P |
ContentType | Journal Article |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.3233/XST-2011-0306 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Engineering Physics |
EISSN | 1095-9114 |
EndPage | 456 |
ExternalDocumentID | 10_3233_XST_2011_0306 25214379 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- --K 0R~ 1B1 1RT 1~5 29L 4.4 4G. 53G 5GY 5VS 7-5 AACTN AAEDT AAFNC AALRI AAQFI AAQXK AAXUO ABDBF ABEFU ABJNI ABMAC ABUBZ ACGFS ACPQW ADBBV ADMUD ADZMO AENEX AFFNX AFRHK AGIAB AHHHB AITUG AKRWK ALMA_UNASSIGNED_HOLDINGS CAG CGR COF CS3 CUY CVF DM4 DU5 EAD EAP EBD EBS ECM EIF EJD EMK EMOBN EPL EST ESX F5P FDB FEDTE FGOYB FIRID G-2 HEI HMK HMO HVGLF HZ~ I-F IHE IL9 IOS LG5 M29 MET MIO MV1 NGNOM NPM O-L O9- P2P R2- RIG ROL RPZ SAE SSZ SV3 TUS UHS WUQ XPP AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c249t-b3ed3b2e6698838a7372213e56348e027d5df00f436122d000334b3ae98b8f943 |
ISSN | 0895-3996 |
IngestDate | Sun May 12 02:25:28 EDT 2024 Fri Aug 23 00:55:55 EDT 2024 Thu May 23 23:21:06 EDT 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 4 |
Keywords | neuromodulation Medtronic neurostimulator radiation oncology Accelerator |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c249t-b3ed3b2e6698838a7372213e56348e027d5df00f436122d000334b3ae98b8f943 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 25214379 |
PQID | 1561973570 |
PQPubID | 23479 |
PageCount | 14 |
ParticipantIDs | proquest_miscellaneous_1561973570 crossref_primary_10_3233_XST_2011_0306 pubmed_primary_25214379 |
PublicationCentury | 2000 |
PublicationDate | 2011-00-00 20110101 |
PublicationDateYYYYMMDD | 2011-01-01 |
PublicationDate_xml | – year: 2011 text: 2011-00-00 |
PublicationDecade | 2010 |
PublicationPlace | Netherlands |
PublicationPlace_xml | – name: Netherlands |
PublicationTitle | Journal of X-ray science and technology |
PublicationTitleAlternate | J Xray Sci Technol |
PublicationYear | 2011 |
SSID | ssj0011588 |
Score | 1.8720167 |
Snippet | Where no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for... OBJECTWhere no society-based or manufacturer guidance on radiation limits to neuromodulation devices is available, this research provides the groundwork for... |
SourceID | proquest crossref pubmed |
SourceType | Aggregation Database Index Database |
StartPage | 443 |
SubjectTerms | Computer Simulation Humans Implantable Neurostimulators Models, Theoretical Phantoms, Imaging Radiotherapy Dosage - standards Radiotherapy Planning, Computer-Assisted - methods Radiotherapy Planning, Computer-Assisted - standards Tomography, X-Ray Computed |
Title | Effects on radiation oncology treatments involving various neuromodulation devices |
URI | https://www.ncbi.nlm.nih.gov/pubmed/25214379 https://search.proquest.com/docview/1561973570 |
Volume | 19 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9swEBdZysb2MLbsK_tCg7EXo9SxJFt-DFu7sNAN2pTlzci2_FLqjCwZbI_7y3dnyaqTpdANjDEykrHux-nudPcTIW85WCG8khWrYl0wUZSSKak006JSOSxYVcixdvjkczw9F58WctHr_e5kLW3W-aj4tbeu5H-kCm0gV6yS_QfJ-kGhAZ5BvnAHCcP9RjI-apMx6mCFHAPW-qsLy6vkc8gx5Qq0UBM6-AG-cUPKiqQcl8vSnd6FxVOoMq6xVRdspX8GbQlQk3T5V0j-Iyy3LpzqcvGDs9HVDhUGVC5sNvds00Qf_cup2xWalPoy-OKbQWFd-No0V3EWfBh14xROgzpFlkoGhlC8pXXTDrpER4UKS9vkVmNhacd3FT2PMBB9vDibMxvk5eEeQu2dhc6nH4LjgwNk0D3D7hl2v0UOoiSVok8OJrPTrzO_FzWWzeml_i8sUysOcLj1_W3L5hp3pTFb5g_IfSdDOrHgeUh6ph6Qex0WygG5c-LyKwbkdpMQXHx_RE4dtuiyph5btMUWvcIW9diiDlt0B1vUYesxOT8-mr-fMnf-BivAKV-znJuS55GJ41QprjSeaBSNuZExF8qEUVLKsgrDSnAwk6MS3Wsucq5NqnJVpYI_If16WZtnhMYVN-O8jFRYoMlY6oiLWHOdhDk4rHEyJO_aucu-WZqVbK-UhuRNO7MZKELc3dK1gX_LxuAJpAmXSTgkT-2U-6EiMFKRePP5TT_zgty1csXrJemvVxvzCqzPdf7aweMPrgCGbg |
link.rule.ids | 315,786,790,4043,27954,27955,27956 |
linkProvider | Library Specific Holdings |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+on+radiation+oncology+treatments+involving+various+neuromodulation+devices&rft.jtitle=Journal+of+X-ray+science+and+technology&rft.au=Gossman%2C+Michael+S.&rft.au=Paralikar%2C+Kunal+J.&rft.au=Hebb%2C+Adam+O.&rft.au=Wilkinson%2C+Jeffrey+D.&rft.date=2011&rft.issn=0895-3996&rft.volume=19&rft.issue=4&rft.spage=443&rft.epage=456&rft_id=info:doi/10.3233%2FXST-2011-0306&rft.externalDBID=n%2Fa&rft.externalDocID=10_3233_XST_2011_0306 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0895-3996&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0895-3996&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0895-3996&client=summon |