Characterization of the mitogen-regulated protein (proliferin) receptor

• Published in: Endocrinology (Philadelphia) Vol. 136; no. 1; p. 283
• Main Authors: Nelson, J T, Rosenzweig, N, Nilsen-Hamilton, M
• Format: Journal Article
• Language: English
• Published: United States 01.01.1995
• Subjects: Animals; Binding, Competitive; DNA - biosynthesis; Female; Gestational Age; Glycoproteins - pharmacology; Growth Substances - pharmacology; Intercellular Signaling Peptides and Proteins; Kinetics; Membranes - metabolism; Mice; Pregnancy; Receptors, Growth Factor - metabolism; Uterus - metabolism

Mitogen-regulated protein (MRP/PLF; also called proliferin) is a member of the PRL-GH family expressed by the placenta in mid-gestation. This report describes an MRP/PLF receptor in uterine membrane preparations from pregnant mice. Peak receptor activity occurred at 11 days of gestation with a disso...