Early and Late Pulmonary AMR Show Distinct Profiles; Clinical and Epigenetic Analyses

• Published in: The Journal of heart and lung transplantation Vol. 39; no. 4; p. S79
• Main Authors: Agbor-Enoh, S., Jang, M., Singh, K., Tunc, I., Pirooznia, M., Seifuddin, F., Ponor, I., Levine, D., Cochrane, A., Philogene, M., Mathews, J., Shah, P., Luikart, H., Khush, K.K., Marboe, C., Berry, G., Valantine, H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2020

Antibody-Mediated Rejection (AMR) that occurs latter in the lung transplant (LTx) course show greater risk of chronic lung allograft dysfunction (CLAD) than early AMR. This suggest distinct mechanisms. This study leverages a large cohort and sensitive genomic tools to profile early and late AMR. 435...