NSC-631570 (Ukrain) in the palliative treatment of pancreatic cancer. Results of a phase II trial

• Published in: Langenbeck's archives of surgery Vol. 386; no. 8; pp. 570 - 574
• Main Authors: Gansauge, Frank, Ramadani, Marco, Pressmar, Jochen, Gansauge, Susanne, Muehling, Bernd, Stecker, Kerstin, Cammerer, Gregor, Leder, Gerd, Beger, Hans G
• Format: Journal Article
• Language: English
• Published: Germany 01.03.2002
• Subjects: Adenocarcinoma - drug therapy; Adenocarcinoma - mortality; Adult; Aged; Aged, 80 and over; Alkaloids - administration & dosage; Alkaloids - therapeutic use; Antimetabolites, Antineoplastic - administration & dosage; Antimetabolites, Antineoplastic - therapeutic use; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - therapeutic use; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Berberine Alkaloids; Deoxycytidine - administration & dosage; Deoxycytidine - analogs & derivatives; Deoxycytidine - therapeutic use; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pancreatic Neoplasms - drug therapy; Pancreatic Neoplasms - mortality; Phenanthridines; Prospective Studies; Survival Analysis; Treatment Outcome

NSC-631570 (Ukrain) is a semisynthetic compound of thiophosphoric acid and the alkaloid chelidonine from the plant Chelidonium majus. It has been used in complementary herbal medicine for more than 20 years for the treatment of benign and malignant tumors. Between August 1999 and June 2001, 90 patie...