Identification of insecticidal molecule aucubin from Metarhizium anisopliae ethyl acetate crude extract against disease mosquito vector
Identification of insecticidal compounds from the entomopathogenic fungus Metarhizium anisopliae crude extract was performed by TLC and column fractionation. From the fractionation four fractions were separated and tested for larvicidal, pupicidal and adulticidal potential against Aedes aegypti , An...
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| Published in | International journal of tropical insect science Vol. 42; no. 5; pp. 3303 - 3318 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Cham
Springer International Publishing
2022
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Identification of insecticidal compounds from the entomopathogenic fungus
Metarhizium anisopliae
crude extract was performed by TLC and column fractionation. From the fractionation four fractions were separated and tested for larvicidal, pupicidal and adulticidal potential against
Aedes aegypti
,
Anopheles stephensi
and
Culex quinquefasciatus
mosquitoes
.
Among the four fractions the fraction-3 was most effective against larvae with LC
50
values, 1.238, 1.300 and 2.899 for pupae, 1.440, 1.657, 2.593 and adult, 1.988, 2.037 and 4.086 µg/ml against
Ae. aegypti
,
An. stephensi
and
Cx. quinquefasciatus
at 24 h post treatment respectively. The effective fraction-3 were charectrized through FT-IR, UV–Vis spectroscopy,
13
C-NMR and
1
H-NMR, HPLC, and LC–MS analysis allowed to identifying the effective compound in fraction-3. Overall, the results confirmed the use of the fungus derived molecules as an active green pesticide against mosquito vectors of public importance and led to the identification of highly effective mosquitocidal products. In particular the toxic activity of aucubin far encompassed that of the large majority of earlier studied microbial insecticides, making this molecule an ideal candidate for the development of insecticides in the “real world”. |
|---|---|
| AbstractList | Identification of insecticidal compounds from the entomopathogenic fungus Metarhizium anisopliae crude extract was performed by TLC and column fractionation. From the fractionation four fractions were separated and tested for larvicidal, pupicidal and adulticidal potential against Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus mosquitoes. Among the four fractions the fraction-3 was most effective against larvae with LC50 values, 1.238, 1.300 and 2.899 for pupae, 1.440, 1.657, 2.593 and adult, 1.988, 2.037 and 4.086 µg/ml against Ae. aegypti, An. stephensi and Cx. quinquefasciatus at 24 h post treatment respectively. The effective fraction-3 were charectrized through FT-IR, UV–Vis spectroscopy, 13C-NMR and 1H-NMR, HPLC, and LC–MS analysis allowed to identifying the effective compound in fraction-3. Overall, the results confirmed the use of the fungus derived molecules as an active green pesticide against mosquito vectors of public importance and led to the identification of highly effective mosquitocidal products. In particular the toxic activity of aucubin far encompassed that of the large majority of earlier studied microbial insecticides, making this molecule an ideal candidate for the development of insecticides in the “real world”. Identification of insecticidal compounds from the entomopathogenic fungus Metarhizium anisopliae crude extract was performed by TLC and column fractionation. From the fractionation four fractions were separated and tested for larvicidal, pupicidal and adulticidal potential against Aedes aegypti , Anopheles stephensi and Culex quinquefasciatus mosquitoes . Among the four fractions the fraction-3 was most effective against larvae with LC 50 values, 1.238, 1.300 and 2.899 for pupae, 1.440, 1.657, 2.593 and adult, 1.988, 2.037 and 4.086 µg/ml against Ae. aegypti , An. stephensi and Cx. quinquefasciatus at 24 h post treatment respectively. The effective fraction-3 were charectrized through FT-IR, UV–Vis spectroscopy, 13 C-NMR and 1 H-NMR, HPLC, and LC–MS analysis allowed to identifying the effective compound in fraction-3. Overall, the results confirmed the use of the fungus derived molecules as an active green pesticide against mosquito vectors of public importance and led to the identification of highly effective mosquitocidal products. In particular the toxic activity of aucubin far encompassed that of the large majority of earlier studied microbial insecticides, making this molecule an ideal candidate for the development of insecticides in the “real world”. |
| Author | Vivekanandhan, P. Swathy, K. Shivakumar, M. S. |
| Author_xml | – sequence: 1 givenname: P. surname: Vivekanandhan fullname: Vivekanandhan, P. organization: Department of Biotechnology, Periyar University, Society for Research and Initiatives for Sustainable Technologies and Institutions, Department of Entomology and Plant Pathology, Faculty of Agriculture, Chiang Mai University, Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes E Alto Douro (UTAD) – sequence: 2 givenname: K. surname: Swathy fullname: Swathy, K. organization: Department of Biotechnology, Periyar University, Society for Research and Initiatives for Sustainable Technologies and Institutions – sequence: 3 givenname: M. S. surname: Shivakumar fullname: Shivakumar, M. S. email: skentomology@gmail.com organization: Department of Biotechnology, Periyar University |
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| Snippet | Identification of insecticidal compounds from the entomopathogenic fungus
Metarhizium anisopliae
crude extract was performed by TLC and column fractionation.... Identification of insecticidal compounds from the entomopathogenic fungus Metarhizium anisopliae crude extract was performed by TLC and column fractionation.... |
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| SubjectTerms | Acetic acid Aedes aegypti Anopheles stephensi Aquatic insects Biomedical and Life Sciences Culex quinquefasciatus Entomology Entomopathogenic fungi Ethyl acetate Fractionation Fungi Infrared spectroscopy Insecticides Larvae Life Sciences Liquid chromatography Metarhizium anisopliae Microorganisms Mosquitoes NMR Nuclear magnetic resonance Original Research Article Pesticides Vectors |
| Title | Identification of insecticidal molecule aucubin from Metarhizium anisopliae ethyl acetate crude extract against disease mosquito vector |
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