High feasibility of salivary therapeutic drug monitoring in linezolid, but lower feasibility in tedizolid: a single-dose study in healthy subjects and a monocentric prospective exploratory study in patients who received linezolid - Kawasuji, Hitoshi; Tsuji, Yasuhiro; Miyaki, Keiko; Aoyama, Takahiko; Kurosaki, Fumihiro; Ezaki, Masayoshi; Koshiyama, Yuki; Takegoshi, Yusuke; Kaneda, Makito; Murai, Yushi; Kimoto, Kou; Nagaoka, Kentaro; et al. (Journal of antimicrobial chemotherapy, 2025)
Keywords: Adult; Aged; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacokinetics; Chromatography, High Pressure Liquid; Drug Monitoring - methods; Feasibility Studies; Female; Healthy Volunteers; Humans; Linezolid - administration & dosage; Linezolid - pharmacokinetics; Male; Middle Aged; Oxazolidinones - administration & dosage; Oxazolidinones - pharmacokinetics; Prospective Studies; Saliva - chemistry; Tetrazoles - administration & dosage; Tetrazoles - pharmacokinetics; Young Adult