Antioxidative Effects of Plant Polyphenols From Protection of G Protein Signaling to Prevention of Age‐Related Pathologies

• Published in: Annals of the New York Academy of Sciences Vol. 1095; no. 1; pp. 449 - 457
• Main Authors: JEFREMOV, VIKTOR, ZILMER, MIHKEL, ZILMER, KERSTI, BOGDANOVIC, NENAD, KARELSON, ELLO
• Format: Journal Article Conference Proceeding
• Language: English
• Published: United States 01.01.2007
• Subjects: Aged, 80 and over; Aging - drug effects; Aging - metabolism; Aging - pathology; Alzheimer Disease - drug therapy; Alzheimer Disease - pathology; Antioxidants - pharmacology; Curcumin - pharmacology; Female; Flavonoids - pharmacology; Genistein - pharmacology; GTP-Binding Proteins - physiology; Humans; Oxidative Stress - drug effects; Phenols - pharmacology; Plant Preparations - pharmacology; Polyphenols; Signal Transduction - drug effects; Stilbenes - pharmacology

Abstract :  The antioxidant potency of three natural polyphenols, resveratrol, curcumin, and genistein, was compared by using the two human models: oxymodified with H 2 O 2 and homocysteine (Hcy) G proteins in the postmortem frontal cortex (FC) membranes of age‐matched control and Alzheimer's d...