Plasmonic Nanobiosensor for Detection of in Aqueous Samples

• Published in: IEEE sensors letters Vol. 8; no. 1; pp. 1 - 4
• Main Authors: Ahmed, Musaddique Mahfuz, Basak, Mitali, Paul, Aman, Singha, Debashreeta, Sinha, Swapnil, Bandyopadhyay, Dipankar
• Format: Journal Article
• Language: English
• Published: Piscataway IEEE 01.01.2024; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: aptamer; biosensor; Biosensors; Chemical and biological sensors; Chemical sensors; E coli; Electric fields; Escherichia coli (EC); gold nanorods (Au NRs); localized surface plasmon resonance (LSPR); Microorganisms; Nanobiotechnology; Nanorods; Pathogens; Plasmonics; Plasmons; Polymerase chain reaction; Public health; Sensors; Surface plasmons; Typhoid
• ISSN: 2475-1472; 2475-1472
• DOI: 10.1109/LSENS.2023.3337938

Escherichia coli is a prevalent pathogen for several fatal ailments, including dysentery, typhoid fever, viral and bacterial gastroenteritis, hepatitis A, diarrhea, and others. Diagnosing a pathogen is indeed a global subject targeting safe public health. Various conventional detection techniques, including bacterial culture, polymerase chain reaction, or enzyme-linked immunosorbent assay, are highly time-consuming and necessitate skilled manpower. This letter demonstrates the development of an efficient plasmonic sensing technique for sensitively detecting Escherichia coli in water. Herein, plasmonic nanostructures-gold nanorods have been immobilized with complementary aptamers for detecting the targeted pathogen up to a limit of detection of 0.91 CFU/mL. The developed platform could be applicable in developing a point-of-detection device for various other pathogen detection.