Visible‐Light‐Mediated Aerobic Oxidative C(sp3)−C(sp3) Bond Cleavage of Morpholine Derivatives Using 4CzIPN as a Photocatalyst
Herein, a metal‐free strategy for the aerobic oxidative cleavage of the inert C(sp3)−C(sp3) bond was developed. Deconstruction of morpholine derivatives was conducted using visible light as an energy source and O2 as an oxidant under mild conditions. This procedure demonstrated suitable selectivity...
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Published in | Advanced synthesis & catalysis Vol. 363; no. 15; pp. 3803 - 3811 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
WEINHEIM
Wiley
03.08.2021
Wiley Subscription Services, Inc |
Subjects | |
Online Access | Get full text |
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Summary: | Herein, a metal‐free strategy for the aerobic oxidative cleavage of the inert C(sp3)−C(sp3) bond was developed. Deconstruction of morpholine derivatives was conducted using visible light as an energy source and O2 as an oxidant under mild conditions. This procedure demonstrated suitable selectivity and functional group tolerance. Moreover, a possible mechanism involving a radical process was proposed based on a series of mechanism exploration and control experiments. |
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ISSN: | 1615-4150 1615-4169 |
DOI: | 10.1002/adsc.202100455 |