A Human Homolog of Angiotensin-converting Enzyme

• Published in: The Journal of biological chemistry Vol. 275; no. 43; pp. 33238 - 33243
• Main Authors: Tipnis, Sarah R., Hooper, Nigel M., Hyde, Ralph, Karran, Eric, Christie, Gary, Turner, Anthony J.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 27.10.2000; American Society for Biochemistry and Molecular Biology

A novel human zinc metalloprotease that has considerable homology to human angiotensin-converting enzyme (ACE) (40% identity and 61% similarity) has been identified. This metalloprotease (angiotensin-converting enzyme homolog (ACEH)) contains a single HEXXH zinc-binding domain and conserves other cr...