Self-healing poly(acrylic acid) hydrogels fabricated by hydrogen bonding and Fe3+ ion cross-linking for cartilage tissue engineering

• Published in: Frontiers of materials science Vol. 17; no. 3
• Main Authors: Kang, Min, Cheng, Yizhu, Hu, Yinchun, Ding, Huixiu, Yang, Hui, Wei, Yan, Huang, Di
• Format: Journal Article
• Language: English
• Published: Beijing Higher Education Press 01.09.2023; Springer Nature B.V
• Subjects: Acrylamide; Biocompatibility; Cartilage; Chemical bonds; Chemistry and Materials Science; Crosslinking; Elongation; Ferric ions; Field emission microscopy; Fourier transforms; Hydrogels; Hydrogen bonding; Materials Science; Mechanical properties; Polyacrylic acid; Research Article; Tensile strength; Tissue engineering; cartilage tissue; hydrogel; self-healing; poly(acrylic acid)

Autonomous self-healing hydrogels were achieved through a dynamic combination of hydrogen bonding and ferric ion (Fe 3+ ) migration. N,N ′-methylenebis (acrylamide) (MBA), a cross-linking agent, was added in this study. Poly(acrylic acid) (PAA)/Fe 3+ and PAA–MBA/Fe 3+ hydrogels were prepared by intr...