Antibody-Free SERS Detection of Severe Fever With Thrombocytopenia Syndrome Virus Using Micron Bowl Array PDMS Substrates

• Published in: IEEE sensors journal Vol. 25; no. 4; pp. 5896 - 5902
• Main Authors: Lin, Ze-Cheng, Lin, Ying-Ting, Tseng, Ching-Yu, Hsu, Wei-Li, Wang, Gou-Jen
• Format: Journal Article
• Language: English
• Published: New York IEEE 15.02.2025; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Antibodies; Arrays; Electroforming; Fever; Free surfaces; Micrometers; Nanoparticles; Nickel; Photolithography; Photoresists; Polydimethylsiloxane; Polydimethylsiloxane (PDMS) surface-enhanced Raman scattering (SERS) substrate; Proteins; Raman scattering; Raman spectra; Resists; Self-assembly; Sensors; SERS; severe fever with thrombocytopenia syndrome virus (SFTSV) detection; Silver; silver nanoparticle (AgNP) deposited microbowl array; Substrates; Thrombocytopenia; Viruses; Viruses (medical); zoonosis

Severe fever with thrombocytopenia syndrome (SFTS) is a newly identified zoonotic infectious disease caused by the SFTS virus (SFTSV). For virus prevention and rapid diagnosis, the development of fast and highly sensitive virus detection methods is necessary. In this study, an antibody-free surface-...