Association Between High Sensitivity Troponin I and NTproBNP With Rejection and Graft Loss in Pediatric Heart Transplant Recipients

• Published in: Pediatric transplantation Vol. 28; no. 7; pp. e14858 - n/a
• Main Authors: Magnetta, Defne A., Jackson, Laurel, Zeevi, Adriana, Turnquist, Heth R., Miller, Susan A., West, Shawn C., Murtagh, Gillian, Feingold, Brian
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.11.2024
• Subjects: acute rejection; Adolescent; Biomarkers; Biomarkers - blood; Blood levels; Child; Child, Preschool; Female; Follow-Up Studies; Graft rejection; Graft Rejection - blood; Graft Rejection - diagnosis; Graft Rejection - etiology; graft survival; heart transplant; Heart transplantation; Heart Transplantation - adverse effects; Heart transplants; Humans; Infant; Male; Natriuretic Peptide, Brain - blood; Pediatrics; Peptide Fragments - blood; Proportional Hazards Models; Troponin I; Troponin I - blood; graft survival; heart transplant; acute rejection; biomarkers

ABSTRACT Background Troponin I is a blood biomarker of cardiac injury and levels measured using a high‐sensitivity assay after pediatric heart transplantation (HT) have not been described. We sought to assess the association between high‐sensitivity troponin I (hsTnI) and N‐terminal pro‐B‐type natri...