A new Centiloid method for 18F-florbetaben and 18F-flutemetamol PET without conversion to PiB

• Published in: European journal of nuclear medicine and molecular imaging Vol. 47; no. 8; pp. 1938 - 1948
• Main Authors: Cho, Soo Hyun, Choe, Yeong Sim, Kim, Hee Jin, Jang, Hyemin, Kim, Yeshin, Kim, Si Eun, Kim, Seung Joo, Kim, Jun Pyo, Jung, Young Hee, Kim, Byeong C., Baker, Suzanne L., Lockhart, Samuel N., Na, Duk L., Park, Seongbeom, Seo, Sang Won
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2020; Springer Nature B.V
• Subjects: Alzheimer's disease; Cardiology; Cognitive ability; Conversion; Imaging; Mathematical analysis; Medicine; Medicine & Public Health; Neurodegenerative diseases; Neurology; Nuclear Medicine; Oncology; Original Article; Orthopedics; Positron emission; Radiology; Tomography; Florbetaben; Alzheimer’s disease; Flutemetamol; Centiloid; Amyloid imaging; Standardization

Purpose We developed a new method to directly calculate Centiloid (CL) units of 18 F-florbetaben (FBB) and 18 F-flutemetamol (FMM) without conversion to the PiB standardized uptake value ratio (SUVR). Methods Paired FBB and FMM PET scans were obtained from 20 Alzheimer’s disease–related cognitive im...