PANoptosis induced by inflammatory cytokines promotes salivary glands radiation injury

• Published in: Oral diseases
• Main Authors: Qu, Yi, Li, Dan, Chen, Guanzheng, Zhao, Shuqi, Han, Zhengxue, Qin, Lizheng
• Format: Journal Article
• Language: English
• Published: Denmark 24.04.2024
• Subjects: inflammatory cytokines; PANoptosis; salivary glands injury; irradiation

Salivary glands are frequently damaged in patients undergoing radiotherapy for head and neck cancer. Whether PANoptosis, which is characterized by pyroptosis, apoptosis, and necroptosis, occurs during radiation injury to the salivary glands and its role remain unclear. Radiation-induced injury model...