New insights into the relationship between airway inflammation and asthma

• Published in: Clinical science (1979) Vol. 103; no. 2; pp. 201 - 211
• Main Authors: WARDLAW, A. J, BRIGHTLING, C. E, GREEN, R, WOLTMANN, G, BRADDING, P, PAVORD, I. D
• Format: Journal Article
• Language: English
• Published: London Portland Press 01.08.2002
• Subjects: Asthma - immunology; Biological and medical sciences; Bronchitis - immunology; Chronic obstructive pulmonary disease, asthma; Eosinophils - immunology; Humans; Mast Cells - immunology; Medical sciences; Muscle, Smooth - immunology; Myositis - immunology; Neutrophils - immunology; Pneumology; Respiratory System - immunology; Respiratory disease; Pathogenesis; Bronchus; Smooth muscle; Inflammation; Obstructive pulmonary disease; Review; Eosinophil; Asthma

Asthma is a condition characterized by variable airflow obstruction, airway hyper-responsiveness (AHR) and airway inflammation which is usually, but not invariably, eosinophilic. Current thoughts on the pathogenesis of asthma are focused on the idea that it is caused by an inappropriate response of...