First-line immunosuppressive therapies for acquired hemophilia A: A 25-year cohort experience and network meta-analysis

• Published in: Thrombosis research Vol. 241; p. 109067
• Main Authors: Rungjirajittranon, Tarinee, Suwanawiboon, Bundarika, Nakkinkun, Yupa, Leelakanok, Nattawut, Kaokunakorn, Thanapon, Chinthammitr, Yingyong, Owattanapanich, Weerapat, Ruchutrakool, Theera
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.09.2024
• Subjects: Acquired hemophilia A; Complete remission; Hemophilia A - blood; Hemophilia A - drug therapy; Humans; Immunosuppressive Agents - therapeutic use; Immunosuppressive treatment; Network Meta-Analysis; Relapse; Retrospective Studies; Acquired hemophilia A; Relapse; Complete remission; Immunosuppressive treatment

Acquired hemophilia A (AHA) presents a significant bleeding risk. Management involves bleeding control and immunosuppressive therapy (IST) to eliminate inhibitors. This study, encompassing a retrospective cohort of 76 newly diagnosed AHA patients (1997–2022), evaluated IST outcomes such as complete...