Is Intraoperative Blood Loss Volume in Elderly Cervical Spine Injury Surgery Greater in Patients with Ankylosis? A Multicenter Survey

• Published in: Spine Surgery and Related Research p. 2023-0118
• Main Authors: Uehara, Masashi, Ikegami, Shota, Takizawa, Takashi, Oba, Hiroki, Yokogawa, Noriaki, Sasagawa, Takeshi, Nakashima, Hiroaki, Segi, Naoki, Ito, Sadayuki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Watanabe, Kota, Nori, Satoshi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Kuroda, Akiyoshi, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, Kato, Satoshi
• Format: Journal Article
• Language: English
• Published: The Japanese Society for Spine Surgery and Related Research 2024
• Subjects: blood loss volume; cervical spine injury; diffuse idiopathic skeletal hyperostosis; elderly patients; ossification of the ligamentum flavum; ossification of the posterior longitudinal ligament
• ISSN: 2432-261X; 2432-261X
• DOI: 10.22603/ssrr.2023-0118

Background: Preoperative estimations of blood loss are important when planning surgery for cervical spine injuries in older adults. The association between ankylosis and blood loss in perioperative management is of particular interest. This multicenter database review aimed to evaluate the impact of ankylosis on surgical blood loss volume in elderly patients with cervical spine injury.Methods: The case histories of 1512 patients with cervical spine injury at among 33 institutions were reviewed. After the exclusion of patients without surgery or whose blood loss or ankylosis status was unclear, 793 participants were available for analysis. Differences in blood loss volume were compared between the Ankylosis (+) group with ankylosis at the cervical level and the Ankylosis (−) group without by the inverse probability of treatment weighting (IPTW) method using a propensity score.Results: Of the 779 patients (mean age: 75.0 ± 6.3 years) eligible for IPTW calculation, 257 (32.4%) had ankylosis at the cervical level. The mean blood loss volume was higher in Ankylosis (+) patients than in Ankylosis (−) patients (P < 0.001). This difference did not reach statistical significance when weighted by background factors, with mean blood loss of 244 mL and 188 mL, respectively, after adjustment.Conclusions: This study revealed that ankylosis was significantly associated with increased blood loss volume when unadjusted by surgical time. Elderly patients with cervical spine injury accompanied by ankylosis appear predisposed to higher bleeding and severe hemorrhage, both as a result of the condition and their particular demographic characteristics.